TY - JOUR
T1 - 4-(3-furyl)-2-(4-methylpiperazino)pyrimidines
T2 - Potent 5-HT(2A) receptor antagonists
AU - Mokrosz, Maria J.
AU - Duszyńska, Beata
AU - Kłodzińska, Aleksandra
AU - Dereń-Wesołek, Anna
AU - Chojnacka-Wójcik, Ewa
AU - Baranowski, Timothy C.
AU - Abdou, Ibrahim M.
AU - Redmore, Naomi P.
AU - Strekowski, Lucjan
N1 - Funding Information:
Acknowledgment. T.C. Baranowski is a recipient of the fellowship of Solvay Pharmaceuticals, Inc., Marietta, Georgia, USA. I.M. Abdou is a Channel student of Tanta University, Tanta, Egypt.
PY - 1997/7/8
Y1 - 1997/7/8
N2 - The title pyrimidines 7-12 are potent 5-HT(2A) receptor ligands with fairly strong behavioral antagonistic activity. A comparison of the structural and binding properties within the entire group of these and other pyrimidines demonstrates two different modes of the bioactive complex formation.
AB - The title pyrimidines 7-12 are potent 5-HT(2A) receptor ligands with fairly strong behavioral antagonistic activity. A comparison of the structural and binding properties within the entire group of these and other pyrimidines demonstrates two different modes of the bioactive complex formation.
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U2 - 10.1016/S0960-894X(97)00291-6
DO - 10.1016/S0960-894X(97)00291-6
M3 - Article
AN - SCOPUS:0343554070
SN - 0960-894X
VL - 7
SP - 1635
EP - 1638
JO - Bioorganic and Medicinal Chemistry Letters
JF - Bioorganic and Medicinal Chemistry Letters
IS - 13
ER -