TY - JOUR
T1 - A comparison between Yfiler® and RM Y-STRs in United Arab Emirates population
AU - Alghafri, R.
AU - Alhammadi, S.
AU - Amiri, K.
N1 - Funding Information:
We would like to humbly thank Dubai Government for enabling grant support for this project. We also would like to acknowledge Abu Dhabi Police General Head Quarters and United Arab Emirates University (Internal Research Grant COS/IRG-2012) for financial and technical support.
Publisher Copyright:
© 2015 Elsevier Ireland Ltd
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Rapidly Mutating Y-STRs (RM Y-STR) were proven to have significantly higher resolution in worldwide populations when compared to commonly used Y-STR kits. In order to contribute to the research that has been conducted so far, RM Y-STRs were investigated in parallel with Yfiler® kit in 327 male individuals from United Arab Emirates population. Such population is considerably isolated where Yfiler® and Powerplex® Y haplotypes were found to be shared between distantly related as well as non-related male individuals. In the present study, a comparison between Y-STR markers included in Yfiler® kit (DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385, DYS393, DYS391, DYS439, DYS635, DYS392, YGATAH4, DYS437, DYS438, DYS448) with RM Y-STRs (DYF387S1, DYF399S1, DYF403S1a/b, DYF404S1, DYS449, DYS518, DYS526a/b, DYS547, DYS570, DYS576, DYS612, DYS626, and DYS627) is conducted. RM Y-STRs were analysed using previously published methods. Forensic parameters were calculated for each set of markers, including discrimination capacity, haplotype diversity and gene diversity, using Arlequin v3.5 software.
AB - Rapidly Mutating Y-STRs (RM Y-STR) were proven to have significantly higher resolution in worldwide populations when compared to commonly used Y-STR kits. In order to contribute to the research that has been conducted so far, RM Y-STRs were investigated in parallel with Yfiler® kit in 327 male individuals from United Arab Emirates population. Such population is considerably isolated where Yfiler® and Powerplex® Y haplotypes were found to be shared between distantly related as well as non-related male individuals. In the present study, a comparison between Y-STR markers included in Yfiler® kit (DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385, DYS393, DYS391, DYS439, DYS635, DYS392, YGATAH4, DYS437, DYS438, DYS448) with RM Y-STRs (DYF387S1, DYF399S1, DYF403S1a/b, DYF404S1, DYS449, DYS518, DYS526a/b, DYS547, DYS570, DYS576, DYS612, DYS626, and DYS627) is conducted. RM Y-STRs were analysed using previously published methods. Forensic parameters were calculated for each set of markers, including discrimination capacity, haplotype diversity and gene diversity, using Arlequin v3.5 software.
KW - Dubai
KW - Mutating
KW - Population
KW - Rapidly
KW - UAE
KW - Y Chromosome
KW - Y-STR
KW - Yfiler
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U2 - 10.1016/j.fsigss.2015.10.012
DO - 10.1016/j.fsigss.2015.10.012
M3 - Article
AN - SCOPUS:84951800624
SN - 1875-1768
VL - 5
SP - e650-e652
JO - Forensic Science International: Genetics Supplement Series
JF - Forensic Science International: Genetics Supplement Series
ER -