A new experimental model for partial ureteric obstruction in sheep

F. M. Abu-Zidan; A. H. Elgazzar; R. H. Bahar; I. M. Francis; M. Sabha; T. Nilsson

doi:10.1023/A:1007164406162

A new experimental model for partial ureteric obstruction in sheep

F. M. Abu-Zidan, A. H. Elgazzar, R. H. Bahar, I. M. Francis, M. Sabha, T. Nilsson

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

This study aimed to develop a new experimental model of partial ureteric obstruction in sheep. Graded obstruction of the ureter using various sized catheters (Fr 3-8) for variable durations up to 6 weeks was performed in 19 sheep. The kidneys were studied by radionuclide diuretic renography for up to 21 weeks and had histopathological examination at the end of the experiment. Catheters of Fr 3 or Fr 5 should be used to block the ureter for a minimum of three weeks to produce sufficient functional and pathological changes to be studied. The advantages and disadvantages of this model are discussed.

Original language	English
Pages (from-to)	149-155
Number of pages	7
Journal	International Urology and Nephrology
Volume	31
Issue number	2
DOIs	https://doi.org/10.1023/A:1007164406162
Publication status	Published - 1999
Externally published	Yes

ASJC Scopus subject areas

Nephrology
Urology

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AU - Elgazzar, A. H.

AU - Bahar, R. H.

AU - Francis, I. M.

AU - Sabha, M.

AU - Nilsson, T.

PY - 1999

Y1 - 1999

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AB - This study aimed to develop a new experimental model of partial ureteric obstruction in sheep. Graded obstruction of the ureter using various sized catheters (Fr 3-8) for variable durations up to 6 weeks was performed in 19 sheep. The kidneys were studied by radionuclide diuretic renography for up to 21 weeks and had histopathological examination at the end of the experiment. Catheters of Fr 3 or Fr 5 should be used to block the ureter for a minimum of three weeks to produce sufficient functional and pathological changes to be studied. The advantages and disadvantages of this model are discussed.

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A new experimental model for partial ureteric obstruction in sheep

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