Thiophenes may be converted to substituted arenes by oxidative cycloaddition to alkynes or by oxidative cycloaddition to alkenes with subsequent oxidative SO-extrusion. Cyano- and acetylamino-groups do not interfere in the reaction and are stable under the reaction conditions. This transformation can be used as a novel route to non-natural aryl-containing amino acids.
|Number of pages||2|
|Journal||Journal of Chemical Research - Part S|
|Publication status||Published - Sept 2003|
- Amino acid
- Thiophene S,S-dioxide
- Thiophene S-oxide
ASJC Scopus subject areas