A series of 7-ω-carboxamidoalkyl-substituted estra-1,3,5(10),6-tetraenes

Thies Thiemann, Kuniharu Umeno, Eiko Inohae, Masao Imai, Yuji Shima, Shuntaro Mataka

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


A number of 7-ω-carboxamidoalkyl-substituted estra-1,3,5(10),6-tetraenes as potential ligands for the estrogen receptor ERα have been prepared using either a conjugate addition of α,ω-iodoalkanenitriles or a Michael addition to steroidal ketone 3 as the key step.

Original languageEnglish
Pages (from-to)1-3
Number of pages3
JournalJournal of Chemical Research - Part S
Issue number1
Publication statusPublished - 2002
Externally publishedYes


  • Conjugate addition
  • Estrogens
  • Estrone
  • Phase transfer catalysis
  • Phosphorane
  • Shapiro reaction
  • Steroids
  • Wittig-olefination

ASJC Scopus subject areas

  • General Chemistry


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