A synthesis of puraquinonic acid

Soleiman Hisaindee, Derrick L.J. Clive

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


2-Methyl-1,4-benzenediol (10) was acylated with α-chloroisobutyroyl chloride and converted by treatment with AlCl3 into the indanone derivative 12, which was elaborated into the substituted indane acid 24. Oxidation then afforded racemic puraquinonic acid.

Original languageEnglish
Pages (from-to)2253-2255
Number of pages3
JournalTetrahedron Letters
Issue number12
Publication statusPublished - Mar 18 2001
Externally publishedYes


  • Antileukemia compound
  • Claisen rearrangement
  • Differentiation inducer
  • Oxidation
  • Quinone

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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