TY - JOUR
T1 - Acetazolamide stimulation test in patients with unilateral internal carotid artery obstructions using transcranial Doppler and 99mTc-HM-PAO- Spect
AU - Rosenkranz, K.
AU - Hierholzer, J.
AU - Langer, R.
AU - Hepp, W.
AU - Palenker, J.
AU - Felix, R.
PY - 1992/1/1
Y1 - 1992/1/1
N2 - Fifteen patients with symptoms of cerebral ischaemia and angiographically confirmed unilateral stenoses or occlusions of the extracranial internal carotid artery (ICA) and 20 controls were studied by a 2 MHz transcranial Doppler (TCD) at rest and after stimulation with 1 g acetazolamide i.v., a cerebral vasodilator. In addition,-the patients underwent 99mTc-HM-PAO- Spect measurement of regional cerebral blood flow (rCBF) at rest and after stimulation with 1 g acetazolamide. In 10 patients with ICA stenoses >80% or occlusions, time-mean velocity (V(mean)) increase and pulsatility index (PI) decrease in the postobstructive middle cerebral artery (MCA) as well as the increase of the ipsilateral rCBF were reduced in comparison with the contralateral side. The remaining 5 patients showed a normal V(mean) increase and PI decrease in TCD.
AB - Fifteen patients with symptoms of cerebral ischaemia and angiographically confirmed unilateral stenoses or occlusions of the extracranial internal carotid artery (ICA) and 20 controls were studied by a 2 MHz transcranial Doppler (TCD) at rest and after stimulation with 1 g acetazolamide i.v., a cerebral vasodilator. In addition,-the patients underwent 99mTc-HM-PAO- Spect measurement of regional cerebral blood flow (rCBF) at rest and after stimulation with 1 g acetazolamide. In 10 patients with ICA stenoses >80% or occlusions, time-mean velocity (V(mean)) increase and pulsatility index (PI) decrease in the postobstructive middle cerebral artery (MCA) as well as the increase of the ipsilateral rCBF were reduced in comparison with the contralateral side. The remaining 5 patients showed a normal V(mean) increase and PI decrease in TCD.
UR - http://www.scopus.com/inward/record.url?scp=0026654199&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026654199&partnerID=8YFLogxK
U2 - 10.1080/01616412.1992.11740033
DO - 10.1080/01616412.1992.11740033
M3 - Article
C2 - 1355870
AN - SCOPUS:0026654199
SN - 0161-6412
VL - 14
SP - 135
EP - 138
JO - Neurological Research
JF - Neurological Research
IS - 2 SUPPL.
ER -