Acid catalysed reaction of estrones with neopentyl glycol under forced conditions

Cristina Oliveira; Goreti Ribeiro Morais; Masao Imai; Eiko Inohae; Chishou Yamamoto; Shuntaro Mataka; Thies Thiemann

doi:10.3184/030823410X12678785299942

Acid catalysed reaction of estrones with neopentyl glycol under forced conditions

Cristina Oliveira
, Goreti Ribeiro Morais
, Masao Imai
, Eiko Inohae
, Chishou Yamamoto
, Shuntaro Mataka
, Thies Thiemann

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Upon reaction with an excess of 2,2-dimethylpropane-1,3-diol (neopentyl glycol) under acid catalysis, estrones form 17-O-[2',2'-dimethyl-2'-(5", 5"-dimethyl-1",3"-dioxanyl)ethyl] substituted estra-3,17β-diols. The reaction represents a formal reduction of a keto function under acidic conditions in the absence of a metal.

Original language	English
Pages (from-to)	158-162
Number of pages	5
Journal	Journal of Chemical Research - Part S
Issue number	3
DOIs	https://doi.org/10.3184/030823410X12678785299942
Publication status	Published - 2010

Keywords

Acid catalysis
Estrone
Reductive etherification

ASJC Scopus subject areas

General Chemistry

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10.3184/030823410X12678785299942

Cite this

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title = "Acid catalysed reaction of estrones with neopentyl glycol under forced conditions",

abstract = "Upon reaction with an excess of 2,2-dimethylpropane-1,3-diol (neopentyl glycol) under acid catalysis, estrones form 17-O-[2',2'-dimethyl-2'-(5{"}, 5{"}-dimethyl-1{"},3{"}-dioxanyl)ethyl] substituted estra-3,17β-diols. The reaction represents a formal reduction of a keto function under acidic conditions in the absence of a metal.",

keywords = "Acid catalysis, Estrone, Reductive etherification",

author = "Cristina Oliveira and Morais, \{Goreti Ribeiro\} and Masao Imai and Eiko Inohae and Chishou Yamamoto and Shuntaro Mataka and Thies Thiemann",

year = "2010",

doi = "10.3184/030823410X12678785299942",

language = "English",

pages = "158--162",

journal = "Journal of Chemical Research - Part S",

issn = "0308-2342",

publisher = "Scientific Reviews 2000 Ltd.",

number = "3",

}

TY - JOUR

T1 - Acid catalysed reaction of estrones with neopentyl glycol under forced conditions

AU - Oliveira, Cristina

AU - Morais, Goreti Ribeiro

AU - Imai, Masao

AU - Inohae, Eiko

AU - Yamamoto, Chishou

AU - Mataka, Shuntaro

AU - Thiemann, Thies

PY - 2010

Y1 - 2010

N2 - Upon reaction with an excess of 2,2-dimethylpropane-1,3-diol (neopentyl glycol) under acid catalysis, estrones form 17-O-[2',2'-dimethyl-2'-(5", 5"-dimethyl-1",3"-dioxanyl)ethyl] substituted estra-3,17β-diols. The reaction represents a formal reduction of a keto function under acidic conditions in the absence of a metal.

AB - Upon reaction with an excess of 2,2-dimethylpropane-1,3-diol (neopentyl glycol) under acid catalysis, estrones form 17-O-[2',2'-dimethyl-2'-(5", 5"-dimethyl-1",3"-dioxanyl)ethyl] substituted estra-3,17β-diols. The reaction represents a formal reduction of a keto function under acidic conditions in the absence of a metal.

KW - Acid catalysis

KW - Estrone

KW - Reductive etherification

UR - https://www.scopus.com/pages/publications/77950660788

UR - https://www.scopus.com/pages/publications/77950660788#tab=citedBy

U2 - 10.3184/030823410X12678785299942

DO - 10.3184/030823410X12678785299942

M3 - Article

AN - SCOPUS:77950660788

SN - 0308-2342

SP - 158

EP - 162

JO - Journal of Chemical Research - Part S

JF - Journal of Chemical Research - Part S

IS - 3

ER -

Acid catalysed reaction of estrones with neopentyl glycol under forced conditions

Abstract

Keywords

ASJC Scopus subject areas

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