Acute rise of pancreatic polypeptide after electroconvulsive therapy

J. M. Allen, T. E. Adrian, P. Cramer, J. Steinert, S. R. Bloom

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Plasma pancreatic polypeptide concentrations rise by 320 ± 81% following administration of electroconvulsive therapy. This rise is observed in the first ten minutes despite premedication of patients with 0.6 mg atropine. Pancreatic polypeptide release is dependent on cholinergic tone and is very sensitive to atropine. The dramatic rise in pancreative polypeptide observed following electroconvulsive therapy probably results from vagal stimulation and reflects insufficient atropine premedication.

Original languageEnglish
Pages (from-to)24-26
Number of pages3
JournalUnknown Journal
Issue number1
Publication statusPublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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