Air pollution and thrombosis: An experimental approach

A. Nemmar, B. Nemery, M. F. Hoylaerts, J. Vermylen

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


Air pollution is associated with cardiovascular mortality. Inhaled ultrafine particles translocate into the blood. Amine-polystyrene ultrafine particles significantly enhance experimental thrombus formation in a damaged hamster vessel and shorten the closure time in the Platelet Function Analyser. Diesel exhaust particles are thrombogenic within one hour of intratracheal instillation and shorten the closure time ex vivo. These experimental observations provide a plausible biological explanation for the epidemiologically established link between air pollution and acute myocardial infarction.

Original languageEnglish
Pages (from-to)349-350
Number of pages2
JournalPathophysiology of Haemostasis and Thrombosis
Issue number5-6
Publication statusPublished - 2002
Externally publishedYes


  • Air pollution
  • Diesel exhaust particles
  • Endothelial injury
  • Myocardial infarction
  • Platelet function analyser
  • Thrombosis
  • Ultrafine particles

ASJC Scopus subject areas

  • Hematology
  • Physiology (medical)


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