Alpha-haemolysin, a possible virulence factor in Proteus morganii

L. Emody, S. Voros, T. Pal

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


In the three animal models described P. morganii strains behaved similarly to E. coli strains studied previously. A marked difference could be observed between the virulence of wild-type haemolytic and nonhaemolytic strains. The rapid appearance of fatal haemorrhagic lung oedema in the lung toxicity assay and the very short survival time in mice infected intraperitoneally with Hly+ strains suggest that a toxic effect may be mainly responsible for the enhanced virulence of alpha-haemolysin-producing strains. The parallel loss of alpha-haemolytic capacity and enhanced virulence in actinomycin-D-treated derivatives also supports this idea.

Original languageEnglish
Pages (from-to)329-331
Number of pages3
JournalFEMS Microbiology Letters
Issue number3
Publication statusPublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology
  • Genetics


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