Ameliorating effect of erythropoietin in a severe case of COVID-19: case report

Mais Mamoon Maufak; Gulfaraz Khan; Ani Purushothaman; Fiaz Ahamed; Mahir Khalil Jallo; Mohammed Rizwan; Sangeeth Kumar; Ahmed Almansouri; Taleb Mohamed Almansoori; Megha Thottappillil Ouseppachen

doi:10.11604/pamj.2022.43.129.35014

Ameliorating effect of erythropoietin in a severe case of COVID-19: case report

Mais Mamoon Maufak
, Gulfaraz Khan
, Ani Purushothaman
, Fiaz Ahamed
, Mahir Khalil Jallo
, Mohammed Rizwan
, Sangeeth Kumar
, Ahmed Almansouri
, Taleb Mohamed Almansoori
, Megha Thottappillil Ouseppachen

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The COVID-19 pandemic is arguably one of the greatest public health crises since the 1918 influenza pandemic. Although several vaccines have been approved and rolled out, effective antiviral treatment options are very limited. Here, we present a case of severe COVID-19 that failed to respond to the standard interventions and continued to deteriorate. On day 22 of his illness, after informed consent, the patient was administered 4000IU of erythropoietin (EPO) subcutaneously, in the hope of improving his O₂ saturation. Positive response was observed in the patient within 24 hours. This prompted us to continued EPO treatment for a total of 42 days until full recovery and discharge. Our findings warrant further studies to ascertain the use of EPO in severe cases COVID-19.

Original language	English
Article number	129
Journal	Pan African Medical Journal
Volume	43
DOIs	https://doi.org/10.11604/pamj.2022.43.129.35014
Publication status	Published - Sept 1 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

COVID-19
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
acute respiratory distress syndrome (ARDS)
case report
erythropoietin

ASJC Scopus subject areas

General Medicine

Access to Document

10.11604/pamj.2022.43.129.35014

Cite this

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title = "Ameliorating effect of erythropoietin in a severe case of COVID-19: case report",

abstract = "The COVID-19 pandemic is arguably one of the greatest public health crises since the 1918 influenza pandemic. Although several vaccines have been approved and rolled out, effective antiviral treatment options are very limited. Here, we present a case of severe COVID-19 that failed to respond to the standard interventions and continued to deteriorate. On day 22 of his illness, after informed consent, the patient was administered 4000IU of erythropoietin (EPO) subcutaneously, in the hope of improving his O2 saturation. Positive response was observed in the patient within 24 hours. This prompted us to continued EPO treatment for a total of 42 days until full recovery and discharge. Our findings warrant further studies to ascertain the use of EPO in severe cases COVID-19.",

keywords = "COVID-19, Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), acute respiratory distress syndrome (ARDS), case report, erythropoietin",

author = "Maufak, \{Mais Mamoon\} and Gulfaraz Khan and Ani Purushothaman and Fiaz Ahamed and Jallo, \{Mahir Khalil\} and Mohammed Rizwan and Sangeeth Kumar and Ahmed Almansouri and Almansoori, \{Taleb Mohamed\} and Ouseppachen, \{Megha Thottappillil\}",

note = "Publisher Copyright: {\textcopyright} Mais Mamoon Maufak et al.",

year = "2022",

month = sep,

day = "1",

doi = "10.11604/pamj.2022.43.129.35014",

language = "English",

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journal = "Pan African Medical Journal",

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T2 - case report

AU - Maufak, Mais Mamoon

AU - Khan, Gulfaraz

AU - Purushothaman, Ani

AU - Ahamed, Fiaz

AU - Jallo, Mahir Khalil

AU - Rizwan, Mohammed

AU - Kumar, Sangeeth

AU - Almansouri, Ahmed

AU - Almansoori, Taleb Mohamed

AU - Ouseppachen, Megha Thottappillil

PY - 2022/9/1

Y1 - 2022/9/1

N2 - The COVID-19 pandemic is arguably one of the greatest public health crises since the 1918 influenza pandemic. Although several vaccines have been approved and rolled out, effective antiviral treatment options are very limited. Here, we present a case of severe COVID-19 that failed to respond to the standard interventions and continued to deteriorate. On day 22 of his illness, after informed consent, the patient was administered 4000IU of erythropoietin (EPO) subcutaneously, in the hope of improving his O2 saturation. Positive response was observed in the patient within 24 hours. This prompted us to continued EPO treatment for a total of 42 days until full recovery and discharge. Our findings warrant further studies to ascertain the use of EPO in severe cases COVID-19.

AB - The COVID-19 pandemic is arguably one of the greatest public health crises since the 1918 influenza pandemic. Although several vaccines have been approved and rolled out, effective antiviral treatment options are very limited. Here, we present a case of severe COVID-19 that failed to respond to the standard interventions and continued to deteriorate. On day 22 of his illness, after informed consent, the patient was administered 4000IU of erythropoietin (EPO) subcutaneously, in the hope of improving his O2 saturation. Positive response was observed in the patient within 24 hours. This prompted us to continued EPO treatment for a total of 42 days until full recovery and discharge. Our findings warrant further studies to ascertain the use of EPO in severe cases COVID-19.

KW - COVID-19

KW - Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)

KW - acute respiratory distress syndrome (ARDS)

KW - case report

KW - erythropoietin

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DO - 10.11604/pamj.2022.43.129.35014

M3 - Article

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AN - SCOPUS:85143763265

SN - 1937-8688

VL - 43

JO - Pan African Medical Journal

JF - Pan African Medical Journal

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ER -

Ameliorating effect of erythropoietin in a severe case of COVID-19: case report

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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