An Accurate Numerical Solution of Biospecific Adsorption in a Stirred Bath

Awad R. Mansour; S. I. Abu-Eishah; A. M. Hussein; A. Maslat

doi:10.1080/01496399008050337

An Accurate Numerical Solution of Biospecific Adsorption in a Stirred Bath

Awad R. Mansour, S. I. Abu-Eishah, A. M. Hussein, A. Maslat

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

A mathematical model describing the kinetics of a biospecific adsorption process (affinity chromatography) in a stirred finite bath has been numerically solved by an efficient computer program. The radial adsorption distribution of β-galactosidase onto immobilized anti-β-galactosidase for different times obtained from the present solution has been satisfactorily compared with previously published experimental data, as well as with the theoretical predictions of Chase's and Arve's models. It is also shown that the present solution is more accurate than the one obtained by Chase. The computer program used in this study is a general one that can be used for any number of solutes and for equilibrium and nonequilibrium conditions.

Original language	English
Pages (from-to)	347-356
Number of pages	10
Journal	Separation Science and Technology
Volume	25
Issue number	3
DOIs	https://doi.org/10.1080/01496399008050337
Publication status	Published - Mar 1 1990
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering
Process Chemistry and Technology
Filtration and Separation

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10.1080/01496399008050337

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abstract = "A mathematical model describing the kinetics of a biospecific adsorption process (affinity chromatography) in a stirred finite bath has been numerically solved by an efficient computer program. The radial adsorption distribution of β-galactosidase onto immobilized anti-β-galactosidase for different times obtained from the present solution has been satisfactorily compared with previously published experimental data, as well as with the theoretical predictions of Chase's and Arve's models. It is also shown that the present solution is more accurate than the one obtained by Chase. The computer program used in this study is a general one that can be used for any number of solutes and for equilibrium and nonequilibrium conditions.",

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PY - 1990/3/1

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N2 - A mathematical model describing the kinetics of a biospecific adsorption process (affinity chromatography) in a stirred finite bath has been numerically solved by an efficient computer program. The radial adsorption distribution of β-galactosidase onto immobilized anti-β-galactosidase for different times obtained from the present solution has been satisfactorily compared with previously published experimental data, as well as with the theoretical predictions of Chase's and Arve's models. It is also shown that the present solution is more accurate than the one obtained by Chase. The computer program used in this study is a general one that can be used for any number of solutes and for equilibrium and nonequilibrium conditions.

AB - A mathematical model describing the kinetics of a biospecific adsorption process (affinity chromatography) in a stirred finite bath has been numerically solved by an efficient computer program. The radial adsorption distribution of β-galactosidase onto immobilized anti-β-galactosidase for different times obtained from the present solution has been satisfactorily compared with previously published experimental data, as well as with the theoretical predictions of Chase's and Arve's models. It is also shown that the present solution is more accurate than the one obtained by Chase. The computer program used in this study is a general one that can be used for any number of solutes and for equilibrium and nonequilibrium conditions.

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An Accurate Numerical Solution of Biospecific Adsorption in a Stirred Bath

Abstract

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