TY - CHAP
T1 - An observational study reveals that neonatal vitamin D is primarily determined by maternal contributions
T2 - Implications of a new assay on the roles of vitamin D forms
AU - Karras, Spyridon N.
AU - Shah, Iltaf
AU - Petroczi, Andrea
AU - Goulis, Dimitrios G.
AU - Bili, Helen
AU - Papadopoulou, Fotini
AU - Harizopoulou, Vikentia
AU - Tarlatzis, Basil C.
AU - Naughton, Declan P.
N1 - Publisher Copyright:
© 2014 by Apple Academic Press, Inc.
PY - 2013/1/1
Y1 - 2013/1/1
N2 - Vitamin D insufficiency and deficiency has been associated with a wide spectrum of diseases, ranging from neurological disorders to chronic inflammatory conditions [1]. The resurgence of rickets in some Western countries highlights the potential risks of not gaining sufficient vitamin D through diet, supplementation or exposure to sunlight [2,3]. Vitamin D deficiency is frequently defined as serum concentrations less than 20 ng/mL with concentrations between 21-29 ng/mL treated as insufficiency and greater than 30 ng/mL as sufficient [4-7]. Recent studies attest to widespread insufficiency of vitamin D in many Western nations, namely the UK, USA and other European countries, including Greece [5,6,8]. Vitamin D deficiency during pregnancy has been associated with maternal morbidity, including gestational diabetes [9] and an increased rate of caesarean section [10]. Likewise, for the neonate, there is a putative association with being small-for-gestational age (SGA) [11]. Finally, as far as children are concerned, impaired neurocognitive development [12] and skeletal problems, such as reduced bone mineral content [13] have been reported.
AB - Vitamin D insufficiency and deficiency has been associated with a wide spectrum of diseases, ranging from neurological disorders to chronic inflammatory conditions [1]. The resurgence of rickets in some Western countries highlights the potential risks of not gaining sufficient vitamin D through diet, supplementation or exposure to sunlight [2,3]. Vitamin D deficiency is frequently defined as serum concentrations less than 20 ng/mL with concentrations between 21-29 ng/mL treated as insufficiency and greater than 30 ng/mL as sufficient [4-7]. Recent studies attest to widespread insufficiency of vitamin D in many Western nations, namely the UK, USA and other European countries, including Greece [5,6,8]. Vitamin D deficiency during pregnancy has been associated with maternal morbidity, including gestational diabetes [9] and an increased rate of caesarean section [10]. Likewise, for the neonate, there is a putative association with being small-for-gestational age (SGA) [11]. Finally, as far as children are concerned, impaired neurocognitive development [12] and skeletal problems, such as reduced bone mineral content [13] have been reported.
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UR - http://www.scopus.com/inward/citedby.url?scp=85055186332&partnerID=8YFLogxK
U2 - 10.1201/b16308
DO - 10.1201/b16308
M3 - Chapter
AN - SCOPUS:85055186332
SN - 9781926895970
SP - 315
EP - 334
BT - Clinical Nutrition
PB - Apple Academic Press
ER -