Abstract
An analytic solution is presented for the simultaneous substrate elimination problem that combines Michaelis-Menten (MM) consumption with an irreversible homo-dimerization process. The implicit solution involves logarithm and inverse tangent functions and perfectly agrees with the numerical solution of the differential equation. A solution is also presented for the generalized dynamical problem that simultaneously combines MM kinetics with first and second-order processes. The exact expressions for the half-life and the area under the curve are also presented for these problems.
Original language | English |
---|---|
Pages (from-to) | 2539-2560 |
Number of pages | 22 |
Journal | Reaction Kinetics, Mechanisms and Catalysis |
Volume | 137 |
Issue number | 5 |
DOIs | |
Publication status | Published - Oct 2024 |
Keywords
- Dimerization
- Enzyme kinetics
- Half-life
- Michaelis-Menten (MM)
- Second-order kinetics
ASJC Scopus subject areas
- Catalysis
- Physical and Theoretical Chemistry