Anticardiolipin antibodies: Prevalence and pregnancy outcome in UAE multiethnic population

Hisham Mohamed Mirghani, Sarath Weerasinghe, Samar Abdulkhalek, Nawal Osman, Rakha AlKilani, Mutairu Ezimokhai

Research output: Contribution to journalArticlepeer-review

Abstract

This cross-sectional case-control study was undertaken to determine the prevalence of anticardiolipin antibodies (ACA) among non-pregnant women, normal pregnancy and complicated pregnancy. The sample was selected from three groups. Group A; non-pregnant women, Group B; healthy pregnant women and Group C included complicated pregnancies. All patients had an initial screening for ACA levels (qualitative assessment). Those who tested positive or borderline were retested (quantitative assessment) after an interval of at least 8 weeks. Data of 496 women were analysed. Fifty-two (10.5%) women had a previous complicated pregnancy. Of the total 496 women only five (1%) were positive for either IgG or IgM. Only one (0.2%) tested strongly positive (IgM). The prevalence of ACA was 0.6% for group A and 1.2% for group B and C. The difference was not statistically significant. In conclusion, this study suggests that the prevalence of ACA in very low in this population. Prenatal complications were not associated with ACA status. The use of prophylactic anticoagulants should be based on confirmed laboratory diagnosis.

Original languageEnglish
Pages (from-to)201-204
Number of pages4
JournalNew Emirates Medical Journal
Volume24
Issue number3
Publication statusPublished - Dec 2006
Externally publishedYes

Keywords

  • Anticardiolipin antibodies
  • Pregnancy outcome

ASJC Scopus subject areas

  • General Medicine

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