Anxiety and depression in Chiari malformation

Esther Lázaro, Maitane García, Imanol Amayra, Juan Francisco López-Paz, Oscar Martínez, Manuel Pérez, Sarah Berrocoso, Mohammad Al Rashaida, Paula Fernández, Alicia Rodríguez, Amaia Jometón, Begoña Ruíz

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


There are few studies that explore the involvement of the cerebellum in the affective area. This study aims to evaluate the affective component and, specifically, the emotional states of depression and anxiety associated with the Chiari malformation, controlling perceived pain. This study included a Chiari group and two control groups, one healthy, the other suffering from Myasthenia gravis, which exhibits a physical component without cerebellar impairment. Each participant completed the Hospital Anxiety and Depression Scale and the Numeric Pain Rating Scale. Scores were significantly higher for the anxiety variable in the Chiari group, either when compared to the control group or the group affected by Myasthenia gravis-controlling the level of headache. The results obtained support previous studies in which the important contribution of the cerebellum to emotional regulation was emphasized.

Original languageEnglish
Pages (from-to)343-348
Number of pages6
JournalJournal of Integrative Neuroscience
Issue number1
Publication statusPublished - Feb 1 2018
Externally publishedYes


  • Anxiety
  • Cerebellum
  • Chiari malformation
  • Depression
  • Observational descriptive study
  • Pain

ASJC Scopus subject areas

  • General Neuroscience


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