Assignment of the mouse homologue of a human MEN1 candidate gene, phospholipase C-β3 (Plcb3), to chromosome region 19B by FISH

A. E. Gobl; B. P. Chowdhary; W. Shu; L. Eriksson; C. Larsson; G. Weber; K. Oberg; B. Skogseid

Assignment of the mouse homologue of a human MEN1 candidate gene, phospholipase C-β3 (Plcb3), to chromosome region 19B by FISH

A. E. Gobl, B. P. Chowdhary, W. Shu, L. Eriksson, C. Larsson, G. Weber, K. Oberg, B. Skogseid

Research output: Contribution to journal › Article › peer-review

Abstract

A recent study using comparative mapping analysis suggests that the proximal segment of mouse chromosome 19 contains the mouse homologs of the human multiple endocrine neoplasia type 1 (MEN1) flanking markers proximal to the locus. We have recently shown that phospholipase C-β3 (PLCB3) is a candidate gene for the MEN1 syndrome. In the present investigation we used fluorescence in situ hybridization with a genomic DNA clone for mouse Plcb3, and mapped the locus to chromosome region 19B. This is in agreement with the comparative mapping of the MEN1 flanking markers in mouse.

Original language	English
Pages (from-to)	257-259
Number of pages	3
Journal	Cytogenetics and Cell Genetics
Volume	71
Issue number	3
Publication status	Published - 1995
Externally published	Yes

ASJC Scopus subject areas

Genetics
Cell Biology

Cite this

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title = "Assignment of the mouse homologue of a human MEN1 candidate gene, phospholipase C-β3 (Plcb3), to chromosome region 19B by FISH",

abstract = "A recent study using comparative mapping analysis suggests that the proximal segment of mouse chromosome 19 contains the mouse homologs of the human multiple endocrine neoplasia type 1 (MEN1) flanking markers proximal to the locus. We have recently shown that phospholipase C-β3 (PLCB3) is a candidate gene for the MEN1 syndrome. In the present investigation we used fluorescence in situ hybridization with a genomic DNA clone for mouse Plcb3, and mapped the locus to chromosome region 19B. This is in agreement with the comparative mapping of the MEN1 flanking markers in mouse.",

author = "Gobl, {A. E.} and Chowdhary, {B. P.} and W. Shu and L. Eriksson and C. Larsson and G. Weber and K. Oberg and B. Skogseid",

year = "1995",

language = "English",

volume = "71",

pages = "257--259",

journal = "Cytogenetics and Cell Genetics",

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T1 - Assignment of the mouse homologue of a human MEN1 candidate gene, phospholipase C-β3 (Plcb3), to chromosome region 19B by FISH

AU - Gobl, A. E.

AU - Chowdhary, B. P.

AU - Shu, W.

AU - Eriksson, L.

AU - Larsson, C.

AU - Weber, G.

AU - Oberg, K.

AU - Skogseid, B.

PY - 1995

Y1 - 1995

N2 - A recent study using comparative mapping analysis suggests that the proximal segment of mouse chromosome 19 contains the mouse homologs of the human multiple endocrine neoplasia type 1 (MEN1) flanking markers proximal to the locus. We have recently shown that phospholipase C-β3 (PLCB3) is a candidate gene for the MEN1 syndrome. In the present investigation we used fluorescence in situ hybridization with a genomic DNA clone for mouse Plcb3, and mapped the locus to chromosome region 19B. This is in agreement with the comparative mapping of the MEN1 flanking markers in mouse.

AB - A recent study using comparative mapping analysis suggests that the proximal segment of mouse chromosome 19 contains the mouse homologs of the human multiple endocrine neoplasia type 1 (MEN1) flanking markers proximal to the locus. We have recently shown that phospholipase C-β3 (PLCB3) is a candidate gene for the MEN1 syndrome. In the present investigation we used fluorescence in situ hybridization with a genomic DNA clone for mouse Plcb3, and mapped the locus to chromosome region 19B. This is in agreement with the comparative mapping of the MEN1 flanking markers in mouse.

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SN - 0301-0171

VL - 71

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JO - Cytogenetics and Cell Genetics

JF - Cytogenetics and Cell Genetics

IS - 3

ER -

Assignment of the mouse homologue of a human MEN1 candidate gene, phospholipase C-β3 (Plcb3), to chromosome region 19B by FISH

Abstract

ASJC Scopus subject areas

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