Association of serum uric acid with body mass index in the United Arab Emirates UAE healthy future pilot study

Mitha Balushi, Amar Ahmad, Syed Javaid, Fabio Piano, Ayesha Dhaheri, Abdishakur Abdulle, Fatma Al-Maskari, Raghib Ali

Research output: Contribution to journalArticlepeer-review

Abstract

Background and Objective: The UAE Healthy Future Study (UAEHFS) is the first large prospective cohort study and one of the few studies in the region which examines causes and risk factors for chronic diseases among the nationals of the UAE. Body Mass Index (BMI) has been showed to be associated with serum uric acid level in many societies. This study investigates the association of serum uric acid with BMI among the UAEHFS pilot participants. Methods: We analyzed the UAEHFS pilot data to investigate the association between serum uric acid levels and BMI. The pridctors were BMI, age, gender and age*gender using multivariate quantile regression models. The quantiles to be estimated was between 25th and 75th varied by 5th. The effect of BMI was estimated with corresponding 95% confidence interval (95% CI). Statistical analysis were performed using statistical software R. Results: Data from 487 eligible participants (67.8% male) with a median age of 30 years (Interquartile-Range: 23–38) was used in the sensitivity analysis. Of these, 406 (83.4%) were included in the complete case analysis. The estimated effect of BMI on the serum uric acid level in the fitted multivariate quantile regression models was positive and statisticaly significant. The estimated effect of BMI in the median (50th quantile) was 0.047 (95% CI: 0.033-0.070). Conclusions: Our Results shows that higher BMI was positive and statisticaly significantly associated with higher serum uric acid levels. Additional research is needed, using the main UAEHFS data (after recruitment is complete), to validate this results. The main finding of this study could add to the future direction of the field of public health research.

Original languageEnglish
Article numberA14
JournalPopulation Medicine
Volume5
DOIs
Publication statusPublished - 2023

ASJC Scopus subject areas

  • Epidemiology
  • Medicine (miscellaneous)
  • Health(social science)
  • Health Policy
  • Health Informatics
  • Public Health, Environmental and Occupational Health

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