TY - GEN
T1 - Bacterial drug delivery systems and nanoparticles
AU - Sharma, R.
AU - Haik, Y.
PY - 2008
Y1 - 2008
N2 - Drug delivery systems use different carrier cage-like structures such as bucky ball, therapeutic spheres, carbon nanotube spheres, tiny-tots, smart dots, paramagnetic nanoparticle cages, dendrimers, liposomes etc. The major developments are reported based on the physical properties of these particles such as paramagnetic, immunity, protein profile, transport dynamics, molecular recognition, receptor compatibility. In this approach drugs can be delivered efficiently at target and tracked in time-dependent manner for drug action at target with serial tissue changes by drug action. Several potential nanoparticles such as iron, zinc, cadmium, silver, gold, rhenium, gadolinium, lanthenum etc. have emerged as bioimaging contrast agents for MRI, radiography, optical, PET, SPECT imaging modalities. In principle, pH dependent delivery systems are designed based on the nanoparticle bound carrier as chemically visible complex by enzyme, chemiluminisence, antigenantibody, fluorescence, dye ratiometric reactions. Major developments are made in therapeutics in tumor, neuropathies, uropathies, cardiovascular diseases, blood and pancreas targeted therapies.
AB - Drug delivery systems use different carrier cage-like structures such as bucky ball, therapeutic spheres, carbon nanotube spheres, tiny-tots, smart dots, paramagnetic nanoparticle cages, dendrimers, liposomes etc. The major developments are reported based on the physical properties of these particles such as paramagnetic, immunity, protein profile, transport dynamics, molecular recognition, receptor compatibility. In this approach drugs can be delivered efficiently at target and tracked in time-dependent manner for drug action at target with serial tissue changes by drug action. Several potential nanoparticles such as iron, zinc, cadmium, silver, gold, rhenium, gadolinium, lanthenum etc. have emerged as bioimaging contrast agents for MRI, radiography, optical, PET, SPECT imaging modalities. In principle, pH dependent delivery systems are designed based on the nanoparticle bound carrier as chemically visible complex by enzyme, chemiluminisence, antigenantibody, fluorescence, dye ratiometric reactions. Major developments are made in therapeutics in tumor, neuropathies, uropathies, cardiovascular diseases, blood and pancreas targeted therapies.
KW - Bioimaging
KW - Drug delivery
KW - Nanoparticles
KW - Therapeutics
UR - http://www.scopus.com/inward/record.url?scp=52649159782&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=52649159782&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:52649159782
SN - 9781420085075
SN - 9781420085044
T3 - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
SP - 61
EP - 64
BT - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
T2 - 2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008
Y2 - 1 June 2008 through 5 June 2008
ER -