Bacterial resistome in different stages of wastewater treatment plant is highly impacted by the abundance of the Pseudomonadota community

Shahana Seher Malik, Dinesh Sanka Loganathachetti, Munawwar Ali Khan, Balamurugan Sadaiappan, Sunil Mundra

Research output: Contribution to journalArticlepeer-review

Abstract

Wastewater treatment plants (WWTPs) are significant sources of antimicrobial resistance (AMR). We studied bacterial communities and antibiotic-resistance genes (ARGs) in different stages of a WWTP in the UAE. We found high levels of extended-spectrum beta-lactamase bacteria in the returned activated sludge (RAS) stage, including Escherichia coli and Aeromonas sobria, resistant to ESBL, ampicillin, and fosfomycin. Bacterial richness was highest in the primary effluent (PE) stage, with distinct community structures influenced by environmental factors. Pseudomonadota dominated across all stages, with Bacteroidota and Bacillota in PE, and Actinomycetota and Pseudomonadota in AS and RAS. Acidovorax sp. showed strong connections with ARGs in PE and RAS, while Delftia acidovorans had the most associations with ARGs in AS. These findings underscore the role of WWTP stages in shaping bacterial communities and ARG abundance, highlighting the potential of certain bacteria in AMR development and dissemination.

Original languageEnglish
Article number101814
JournalBioresource Technology Reports
Volume26
DOIs
Publication statusPublished - Jun 2024

Keywords

  • Activated sludge
  • Antimicrobial resistance
  • Bacterial communities
  • Metagenomics
  • Wastewater treatment plant

ASJC Scopus subject areas

  • Bioengineering
  • Environmental Engineering
  • Renewable Energy, Sustainability and the Environment
  • Waste Management and Disposal

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