Benzothieno and benzofurano annelated estranes

Masataka Watanabe; Shuntaro Mataka; Thies Thiemann

doi:10.1016/j.steroids.2005.06.001

Benzothieno and benzofurano annelated estranes

Masataka Watanabe
, Shuntaro Mataka
, Thies Thiemann

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

The preparation of estrone derived benzothieno- and benzofurano fused steroids is described. Keystep is an intramolecular thienyl(/furyl)-ene-yne cyclization of 16-ethynyl-17-heterarylestra-1,3,5(10),16-tetraenes. The cyclization was carried out under Pt as well as under Ru catalysis.

Original language	English
Pages (from-to)	856-866
Number of pages	11
Journal	Steroids
Volume	70
Issue number	13
DOIs	https://doi.org/10.1016/j.steroids.2005.06.001
Publication status	Published - Dec 1 2005
Externally published	Yes

Keywords

Cyclization
Diene-ynes
Estranes
Fused steroids
Heteroaryl-ene-ynes
Synthesis

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Endocrinology
Pharmacology
Clinical Biochemistry
Organic Chemistry

Access to Document

10.1016/j.steroids.2005.06.001

Cite this

@article{dff5ff564ab54643ab5e7e640ad280bb,

title = "Benzothieno and benzofurano annelated estranes",

abstract = "The preparation of estrone derived benzothieno- and benzofurano fused steroids is described. Keystep is an intramolecular thienyl(/furyl)-ene-yne cyclization of 16-ethynyl-17-heterarylestra-1,3,5(10),16-tetraenes. The cyclization was carried out under Pt as well as under Ru catalysis.",

keywords = "Cyclization, Diene-ynes, Estranes, Fused steroids, Heteroaryl-ene-ynes, Synthesis",

author = "Masataka Watanabe and Shuntaro Mataka and Thies Thiemann",

note = "Funding Information: The authors thank Prof. Dr. I. Mochida and Prof. Dr. S.-H. Yoon of Kyushu University for generous gifts of CNF [CN28-580 °C, HCl treated], and the catalysts 10 wt\% Pt on CNF and 20 wt\% PtRu on CNF. Ms. Yasuko Tanaka has carried out MS and HRMS (EI and FAB) measurements. Elemental analyses were performed at the Center for Instrumental Analysis, Hakozaki Campus, Kyushu University. Part of this work has been carried out within the framework of a CREST program. Financial support from the Japan Science and Technology Corporation (JST) is gratefully acknowledged.",

year = "2005",

month = dec,

day = "1",

doi = "10.1016/j.steroids.2005.06.001",

language = "English",

volume = "70",

pages = "856--866",

journal = "Steroids",

issn = "0039-128X",

publisher = "Elsevier Inc.",

number = "13",

}

TY - JOUR

T1 - Benzothieno and benzofurano annelated estranes

AU - Watanabe, Masataka

AU - Mataka, Shuntaro

AU - Thiemann, Thies

N1 - Funding Information: The authors thank Prof. Dr. I. Mochida and Prof. Dr. S.-H. Yoon of Kyushu University for generous gifts of CNF [CN28-580 °C, HCl treated], and the catalysts 10 wt% Pt on CNF and 20 wt% PtRu on CNF. Ms. Yasuko Tanaka has carried out MS and HRMS (EI and FAB) measurements. Elemental analyses were performed at the Center for Instrumental Analysis, Hakozaki Campus, Kyushu University. Part of this work has been carried out within the framework of a CREST program. Financial support from the Japan Science and Technology Corporation (JST) is gratefully acknowledged.

PY - 2005/12/1

Y1 - 2005/12/1

N2 - The preparation of estrone derived benzothieno- and benzofurano fused steroids is described. Keystep is an intramolecular thienyl(/furyl)-ene-yne cyclization of 16-ethynyl-17-heterarylestra-1,3,5(10),16-tetraenes. The cyclization was carried out under Pt as well as under Ru catalysis.

AB - The preparation of estrone derived benzothieno- and benzofurano fused steroids is described. Keystep is an intramolecular thienyl(/furyl)-ene-yne cyclization of 16-ethynyl-17-heterarylestra-1,3,5(10),16-tetraenes. The cyclization was carried out under Pt as well as under Ru catalysis.

KW - Cyclization

KW - Diene-ynes

KW - Estranes

KW - Fused steroids

KW - Heteroaryl-ene-ynes

KW - Synthesis

UR - https://www.scopus.com/pages/publications/27644585901

UR - https://www.scopus.com/pages/publications/27644585901#tab=citedBy

U2 - 10.1016/j.steroids.2005.06.001

DO - 10.1016/j.steroids.2005.06.001

M3 - Article

C2 - 16045951

AN - SCOPUS:27644585901

SN - 0039-128X

VL - 70

SP - 856

EP - 866

JO - Steroids

JF - Steroids

IS - 13

ER -

Benzothieno and benzofurano annelated estranes

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this