Biosynthesis and metabolism of cyclopropane rings in natural compounds

Ludger A. Wessjohann, Wolfgang Brandt, Thies Thiemann

Research output: Contribution to journalArticlepeer-review

563 Citations (Scopus)


Cyclopropane subunits occur in many natural products of secondary metabolism. Majority of cyclopropane-containing natural compounds have been isolated from plants, fungi, or microorganisms. This review focuses on the principal mechanisms of the biosynthesis and metabolism of cyclopropane-containing natural products and selected related compounds. Focus is on the formation, transformation, and degradation of the cyclopropane moiety itself.

Original languageEnglish
Pages (from-to)1625-1647
Number of pages23
JournalChemical Reviews
Issue number4
Publication statusPublished - Apr 2003
Externally publishedYes

ASJC Scopus subject areas

  • General Chemistry


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