Biosynthesis and metabolism of cyclopropane rings in natural compounds

Ludger A. Wessjohann; Wolfgang Brandt; Thies Thiemann

doi:10.1021/cr0100188

Biosynthesis and metabolism of cyclopropane rings in natural compounds

Ludger A. Wessjohann, Wolfgang Brandt, Thies Thiemann

Research output: Contribution to journal › Article › peer-review

543 Citations (Scopus)

Abstract

Cyclopropane subunits occur in many natural products of secondary metabolism. Majority of cyclopropane-containing natural compounds have been isolated from plants, fungi, or microorganisms. This review focuses on the principal mechanisms of the biosynthesis and metabolism of cyclopropane-containing natural products and selected related compounds. Focus is on the formation, transformation, and degradation of the cyclopropane moiety itself.

Original language	English
Pages (from-to)	1625-1647
Number of pages	23
Journal	Chemical Reviews
Volume	103
Issue number	4
DOIs	https://doi.org/10.1021/cr0100188
Publication status	Published - Apr 2003
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)

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10.1021/cr0100188

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title = "Biosynthesis and metabolism of cyclopropane rings in natural compounds",

abstract = "Cyclopropane subunits occur in many natural products of secondary metabolism. Majority of cyclopropane-containing natural compounds have been isolated from plants, fungi, or microorganisms. This review focuses on the principal mechanisms of the biosynthesis and metabolism of cyclopropane-containing natural products and selected related compounds. Focus is on the formation, transformation, and degradation of the cyclopropane moiety itself.",

author = "Wessjohann, {Ludger A.} and Wolfgang Brandt and Thies Thiemann",

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AU - Brandt, Wolfgang

AU - Thiemann, Thies

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N2 - Cyclopropane subunits occur in many natural products of secondary metabolism. Majority of cyclopropane-containing natural compounds have been isolated from plants, fungi, or microorganisms. This review focuses on the principal mechanisms of the biosynthesis and metabolism of cyclopropane-containing natural products and selected related compounds. Focus is on the formation, transformation, and degradation of the cyclopropane moiety itself.

AB - Cyclopropane subunits occur in many natural products of secondary metabolism. Majority of cyclopropane-containing natural compounds have been isolated from plants, fungi, or microorganisms. This review focuses on the principal mechanisms of the biosynthesis and metabolism of cyclopropane-containing natural products and selected related compounds. Focus is on the formation, transformation, and degradation of the cyclopropane moiety itself.

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Biosynthesis and metabolism of cyclopropane rings in natural compounds

Abstract

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