Cardiac output decline in prolonged dynamic exercise is affected by the exercise mode

George P. Nassis, Nickos D. Geladas

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)


The aim of this study was to compare the cardiovascular responses to prolonged submaximal cycling and running. Eleven males [maximal oxygen uptake (V̇O2max): 3.58±0.15 l min-1 for running and 3.84±0.16 l min-1 for cycling; mean±SE] either cycled (C) or ran (R) for 90 min at 60% of mode-specific V̇O2max, on two randomly assigned occasions. Cardiac output declined after 85 min of exercise in C (-1.9±0.5 l min-1, P<0.01) but not in R, as a result of a more pronounced decrease in stroke volume in the former exercise mode (-22.7±3.8 ml beat-1 vs -14.3±1.9 ml beat-1, P<0.01) since heart rate did not differ between trials. Stroke volume responses were despite a higher level of dehydration (-3.3±0.2% in R vs -2.8±0.2% in C, P<0.05) and hyperthermia in R (39.6±0.1 vs 38.8±0.1°C in C at 90 min, P<0.01). Finally, mean skin blood flow was lower in R than C (72±8 vs 89±10%; P<0.05). In conclusion, stroke volume and cardiac output decline was more pronounced in cycling than in running despite lower dehydration and rectal temperature in the former exercise mode.

Original languageEnglish
Pages (from-to)398-404
Number of pages7
JournalPflugers Archiv European Journal of Physiology
Issue number3
Publication statusPublished - 2002
Externally publishedYes


  • Cardiac output
  • Exercise mode
  • Hyperthermia
  • Skin blood flow
  • Stroke volume

ASJC Scopus subject areas

  • Physiology
  • Clinical Biochemistry
  • Physiology (medical)


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