Cardiovascular friendly natural products: A promising approach in the management of CVD

Santosh K. Shukla, Shipra Gupta, Shreesh K. Ojha, Suman B. Sharma

Research output: Contribution to journalReview articlepeer-review

89 Citations (Scopus)


Natural products play an important role as nutritional supplements and provide potential health benefits in cardiovascular diseases (CVD). Compiling data from experimental, epidemiological and clinical studies indicates that dietary nutrients have profound cardioprotective effects in the primary as well as secondary prevention of coronary heart disease, hence they are considered as cardiovascular friendly natural products. The mechanism of cardioprotection produced by dietary nutritional supplements such as flavonoids (citrus fruits, pulses, red wine, tea and cocoa), olive oil, omega-3 (-3) fatty acids (fish oil and fish-based products), lycopene (tomato and tomato-based products), resveratrol (grapes and red wine), coffee, and soy in the prevention and treatment of cardiovascular disorders have been discussed in the present review, with the emphasis of epidemiological and clinical studies. Based on the intriguing results of various studies, prophylactic and therapeutic potential of cardiovascular friendly natural products have been suggested. The supplementation of cardiovascular friendly natural products needs to be considered in all populations who have high prevalence of CVD.

Original languageEnglish
Pages (from-to)873-898
Number of pages26
JournalNatural Product Research
Issue number9
Publication statusPublished - May 2010
Externally publishedYes


  • Anti-inflammatory activity
  • Anti-thrombotic activity
  • Antioxidant activity
  • Cardiovascular diseases
  • Natural products

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry


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