Cellular origin of human pancreatic polypeptide (HPP) in endocrine tumours of the pancreas

Ph Heitz; Julia M. Polak; S. R. Bloom; T. E. Adrian; A. G.E. Pearse

doi:10.1007/BF02899159

Cellular origin of human pancreatic polypeptide (HPP) in endocrine tumours of the pancreas

Ph Heitz, Julia M. Polak, S. R. Bloom, T. E. Adrian, A. G.E. Pearse

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

Pancreatic polypeptide (HPP) producing cells were detected in 23 out of 36 endocrine tumours of the pancreas. In all tumours shown to be producing two hormones it was possible to demonstrate two different cell types by immunocytochemistry and/or electron microscopy. The D₁ cell was identified as the source of HPP in tumours.

Original language	English
Pages (from-to)	259-265
Number of pages	7
Journal	Virchows Archiv B Cell Pathology
Volume	21
Issue number	1
DOIs	https://doi.org/10.1007/BF02899159
Publication status	Published - Dec 1976
Externally published	Yes

Keywords

D cell of the pancreas
Endocrine pancreatic tumours
Human pancreatic polypeptide
Immunocytochemistry and electron microscopy

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1007/BF02899159

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title = "Cellular origin of human pancreatic polypeptide (HPP) in endocrine tumours of the pancreas",

abstract = "Pancreatic polypeptide (HPP) producing cells were detected in 23 out of 36 endocrine tumours of the pancreas. In all tumours shown to be producing two hormones it was possible to demonstrate two different cell types by immunocytochemistry and/or electron microscopy. The D1 cell was identified as the source of HPP in tumours.",

keywords = "D cell of the pancreas, Endocrine pancreatic tumours, Human pancreatic polypeptide, Immunocytochemistry and electron microscopy",

author = "Ph Heitz and Polak, {Julia M.} and Bloom, {S. R.} and Adrian, {T. E.} and Pearse, {A. G.E.}",

year = "1976",

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AU - Bloom, S. R.

AU - Adrian, T. E.

AU - Pearse, A. G.E.

PY - 1976/12

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N2 - Pancreatic polypeptide (HPP) producing cells were detected in 23 out of 36 endocrine tumours of the pancreas. In all tumours shown to be producing two hormones it was possible to demonstrate two different cell types by immunocytochemistry and/or electron microscopy. The D1 cell was identified as the source of HPP in tumours.

AB - Pancreatic polypeptide (HPP) producing cells were detected in 23 out of 36 endocrine tumours of the pancreas. In all tumours shown to be producing two hormones it was possible to demonstrate two different cell types by immunocytochemistry and/or electron microscopy. The D1 cell was identified as the source of HPP in tumours.

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KW - Endocrine pancreatic tumours

KW - Human pancreatic polypeptide

KW - Immunocytochemistry and electron microscopy

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Cellular origin of human pancreatic polypeptide (HPP) in endocrine tumours of the pancreas

Abstract

Keywords

ASJC Scopus subject areas

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