Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries

Mohamed Arafah; Ali T. Al-Hinai; Wael Al Mahmeed; Khalid Al-Rasadi; Omer Al Tamimi; Shorook Al Herz; Faisal Al Anazi; Khalid Al Nemer; Othman Metwally; Akram Alkhadra; Mohammed Fakhry; Hossam Elghetany; Abdel Razak Medani; Afzal Hussein Yusufali; Obaid Al Jassim; Omar Al Hallaq; Fahad Omar Ahmed S. Baslaib; Mahmoud Alawadhi; Haitham Amin; Khamis Al-Hashmi; Abdullah Shehab

doi:10.1177/0003319713512414

Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries

Mohamed Arafah
, Ali T. Al-Hinai
, Wael Al Mahmeed
, Khalid Al-Rasadi
, Omer Al Tamimi
, Shorook Al Herz
, Faisal Al Anazi
, Khalid Al Nemer
, Othman Metwally
, Akram Alkhadra
, Mohammed Fakhry
, Hossam Elghetany
, Abdel Razak Medani
, Afzal Hussein Yusufali
, Obaid Al Jassim
, Omar Al Hallaq
, Fahad Omar Ahmed S. Baslaib
, Mahmoud Alawadhi
, Haitham Amin
, Khamis Al-Hashmi

Abdullah Shehab

Department of Internal Medicine

Research output: Contribution to journal › Review article › peer-review

35 Citations (Scopus)

Abstract

The Centralized pan-Middle East Survey on the undertreatment of hypercholesterolemia (CEPHEUS) survey evaluated the attainment of low-density lipoprotein cholesterol (LDL-C) goals among patients on lipid-lowering drugs (LLDs) according to the updated National Cholesterol Education Program (NCEP)-Adult Treatment Panel (ATP-III) guideline. The survey was conducted in 6 Arabian Gulf countries. Patients aged ≥18 years on LLDs for at least ≥3 months (stable medication for ≥6 weeks) were recruited. Fasting blood samples were collected at a single visit. In this survey, 5276 (58.2% male) patients were included in the final analysis. The LDL-C goal was attained in 91.1% of low-risk, 52.7% of high-risk, and 32.0% in very-high-risk categories. Goal attainment was directly related to female gender, age <40 years, history of diabetes, and family history of cardiovascular disease. The results of this survey highlight the suboptimal management of hypercholesterolemia across Arabian Gulf countries.

Original language	English
Pages (from-to)	919-926
Number of pages	8
Journal	Angiology
Volume	65
Issue number	10
DOIs	https://doi.org/10.1177/0003319713512414
Publication status	Published - Nov 12 2014

Keywords

Arabian Gulf countries
cardiovascular
coronary
guidelines
hypercholesterolemia
lipids
low-density lipoprotein

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1177/0003319713512414

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Arafah, M., Al-Hinai, A. T., Mahmeed, W. A., Al-Rasadi, K., Tamimi, O. A., Herz, S. A., Anazi, F. A., Nemer, K. A., Metwally, O., Alkhadra, A., Fakhry, M., Elghetany, H., Medani, A. R., Yusufali, A. H., Jassim, O. A., Hallaq, O. A., Baslaib, F. O. A. S., Alawadhi, M., Amin, H., ... Shehab, A. (2014). Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries. Angiology, 65(10), 919-926. https://doi.org/10.1177/0003319713512414

Arafah, M, Al-Hinai, AT, Mahmeed, WA, Al-Rasadi, K, Tamimi, OA, Herz, SA, Anazi, FA, Nemer, KA, Metwally, O, Alkhadra, A, Fakhry, M, Elghetany, H, Medani, AR, Yusufali, AH, Jassim, OA, Hallaq, OA, Baslaib, FOAS, Alawadhi, M, Amin, H, Al-Hashmi, K & Shehab, A 2014, 'Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries', Angiology, vol. 65, no. 10, pp. 919-926. https://doi.org/10.1177/0003319713512414

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title = "Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries",

abstract = "The Centralized pan-Middle East Survey on the undertreatment of hypercholesterolemia (CEPHEUS) survey evaluated the attainment of low-density lipoprotein cholesterol (LDL-C) goals among patients on lipid-lowering drugs (LLDs) according to the updated National Cholesterol Education Program (NCEP)-Adult Treatment Panel (ATP-III) guideline. The survey was conducted in 6 Arabian Gulf countries. Patients aged ≥18 years on LLDs for at least ≥3 months (stable medication for ≥6 weeks) were recruited. Fasting blood samples were collected at a single visit. In this survey, 5276 (58.2\% male) patients were included in the final analysis. The LDL-C goal was attained in 91.1\% of low-risk, 52.7\% of high-risk, and 32.0\% in very-high-risk categories. Goal attainment was directly related to female gender, age <40 years, history of diabetes, and family history of cardiovascular disease. The results of this survey highlight the suboptimal management of hypercholesterolemia across Arabian Gulf countries.",

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doi = "10.1177/0003319713512414",

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AU - Al-Hinai, Ali T.

AU - Mahmeed, Wael Al

AU - Al-Rasadi, Khalid

AU - Tamimi, Omer Al

AU - Herz, Shorook Al

AU - Anazi, Faisal Al

AU - Nemer, Khalid Al

AU - Metwally, Othman

AU - Alkhadra, Akram

AU - Fakhry, Mohammed

AU - Elghetany, Hossam

AU - Medani, Abdel Razak

AU - Yusufali, Afzal Hussein

AU - Jassim, Obaid Al

AU - Hallaq, Omar Al

AU - Baslaib, Fahad Omar Ahmed S.

AU - Alawadhi, Mahmoud

AU - Amin, Haitham

AU - Al-Hashmi, Khamis

AU - Shehab, Abdullah

PY - 2014/11/12

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N2 - The Centralized pan-Middle East Survey on the undertreatment of hypercholesterolemia (CEPHEUS) survey evaluated the attainment of low-density lipoprotein cholesterol (LDL-C) goals among patients on lipid-lowering drugs (LLDs) according to the updated National Cholesterol Education Program (NCEP)-Adult Treatment Panel (ATP-III) guideline. The survey was conducted in 6 Arabian Gulf countries. Patients aged ≥18 years on LLDs for at least ≥3 months (stable medication for ≥6 weeks) were recruited. Fasting blood samples were collected at a single visit. In this survey, 5276 (58.2% male) patients were included in the final analysis. The LDL-C goal was attained in 91.1% of low-risk, 52.7% of high-risk, and 32.0% in very-high-risk categories. Goal attainment was directly related to female gender, age <40 years, history of diabetes, and family history of cardiovascular disease. The results of this survey highlight the suboptimal management of hypercholesterolemia across Arabian Gulf countries.

AB - The Centralized pan-Middle East Survey on the undertreatment of hypercholesterolemia (CEPHEUS) survey evaluated the attainment of low-density lipoprotein cholesterol (LDL-C) goals among patients on lipid-lowering drugs (LLDs) according to the updated National Cholesterol Education Program (NCEP)-Adult Treatment Panel (ATP-III) guideline. The survey was conducted in 6 Arabian Gulf countries. Patients aged ≥18 years on LLDs for at least ≥3 months (stable medication for ≥6 weeks) were recruited. Fasting blood samples were collected at a single visit. In this survey, 5276 (58.2% male) patients were included in the final analysis. The LDL-C goal was attained in 91.1% of low-risk, 52.7% of high-risk, and 32.0% in very-high-risk categories. Goal attainment was directly related to female gender, age <40 years, history of diabetes, and family history of cardiovascular disease. The results of this survey highlight the suboptimal management of hypercholesterolemia across Arabian Gulf countries.

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KW - cardiovascular

KW - coronary

KW - guidelines

KW - hypercholesterolemia

KW - lipids

KW - low-density lipoprotein

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JO - Angiology

JF - Angiology

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ER -

Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries

Abstract

Keywords

ASJC Scopus subject areas

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