Chemiluminescence of lucigenin-tetracycline and its application for sensitive determination of procyanidin

  • Shuai Quan
  • , Kaixiang Ji
  • , Fangshuo Liu
  • , Tesfaye Hailemariam Barkae
  • , Mohamed Ibrahim Halawa
  • , Saima Hanif
  • , Baohua Lou
  • , Jianping Li
  • , Guobao Xu

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Tetracycline was reported to trigger intense lucigenin chemiluminescence (CL). Based on its significant quenching to lucigenin-tetracycline CL, procyanidin was detected. The mechanism of the lucigenin-tetracycline CL and its quenching by procyanidin were proposed. Under the optimum conditions, the calibration curve is linear in the range of 10-1000 nM for procyanidin with a detection limit of 4.4 nM. The RSD for nine replicate determinations of procyanidin was less than 1.7%. Moreover, this method was satisfactorily applied to the determination of procyanidin in human urine samples and health food capsule of grape seed.

Original languageEnglish
Pages (from-to)293-302
Number of pages10
JournalJournal of Food and Drug Analysis
Volume30
Issue number2
DOIs
Publication statusPublished - 2022
Externally publishedYes

Keywords

  • Chemiluminescence
  • Lucigenin
  • Procyanidin
  • Tetracycline

ASJC Scopus subject areas

  • Food Science
  • Pharmacology

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