Cognitive decline: A vitamin B perspective

Kathleen Mikkelsen; Lily Stojanovska; Kathy Tangalakis; Marijan Bosevski; Vasso Apostolopoulos

doi:10.1016/j.maturitas.2016.08.001

Cognitive decline: A vitamin B perspective

Kathleen Mikkelsen, Lily Stojanovska, Kathy Tangalakis, Marijan Bosevski, Vasso Apostolopoulos

Research output: Contribution to journal › Review article › peer-review

45 Citations (Scopus)

Abstract

Cognitive decline is one of the major causes of disability in older people. A high level of homocysteine, a byproduct of vitamin B, has been linked to brain atrophy, which itself is a precursor to cognitive decline leading to dementia and Alzheimer's disease. In addition, a low level of vitamin B is often noted in patients with dementia and Alzheimer's disease and its supplementation has been shown to improve memory and to slow the progress of brain atrophy. This information may aid in the use of vitamin B as a preventative measure against severe cognitive decline, and thus reduce the onset of conditions such as dementia and Alzheimer's disease.

Original language	English
Pages (from-to)	108-113
Number of pages	6
Journal	Maturitas
Volume	93
DOIs	https://doi.org/10.1016/j.maturitas.2016.08.001
Publication status	Published - Nov 1 2016
Externally published	Yes

Keywords

Ageing
Gerontology
Immune cells
Immune system
Inflammation

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Obstetrics and Gynaecology

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10.1016/j.maturitas.2016.08.001

Cite this

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title = "Cognitive decline: A vitamin B perspective",

abstract = "Cognitive decline is one of the major causes of disability in older people. A high level of homocysteine, a byproduct of vitamin B, has been linked to brain atrophy, which itself is a precursor to cognitive decline leading to dementia and Alzheimer's disease. In addition, a low level of vitamin B is often noted in patients with dementia and Alzheimer's disease and its supplementation has been shown to improve memory and to slow the progress of brain atrophy. This information may aid in the use of vitamin B as a preventative measure against severe cognitive decline, and thus reduce the onset of conditions such as dementia and Alzheimer's disease.",

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T1 - Cognitive decline

T2 - A vitamin B perspective

AU - Mikkelsen, Kathleen

AU - Stojanovska, Lily

AU - Tangalakis, Kathy

AU - Bosevski, Marijan

AU - Apostolopoulos, Vasso

N1 - Funding Information: LS and VA were supported by the Rebecca L Cooper Medical Research Foundation and the Centre for Chronic Disease , College of Health and Biomedicine, Victoria University, Australia. Publisher Copyright: © 2016 Elsevier Ireland Ltd

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Cognitive decline is one of the major causes of disability in older people. A high level of homocysteine, a byproduct of vitamin B, has been linked to brain atrophy, which itself is a precursor to cognitive decline leading to dementia and Alzheimer's disease. In addition, a low level of vitamin B is often noted in patients with dementia and Alzheimer's disease and its supplementation has been shown to improve memory and to slow the progress of brain atrophy. This information may aid in the use of vitamin B as a preventative measure against severe cognitive decline, and thus reduce the onset of conditions such as dementia and Alzheimer's disease.

AB - Cognitive decline is one of the major causes of disability in older people. A high level of homocysteine, a byproduct of vitamin B, has been linked to brain atrophy, which itself is a precursor to cognitive decline leading to dementia and Alzheimer's disease. In addition, a low level of vitamin B is often noted in patients with dementia and Alzheimer's disease and its supplementation has been shown to improve memory and to slow the progress of brain atrophy. This information may aid in the use of vitamin B as a preventative measure against severe cognitive decline, and thus reduce the onset of conditions such as dementia and Alzheimer's disease.

KW - Ageing

KW - Gerontology

KW - Immune cells

KW - Immune system

KW - Inflammation

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DO - 10.1016/j.maturitas.2016.08.001

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JO - Maturitas

JF - Maturitas

ER -

Cognitive decline: A vitamin B perspective

Abstract

Keywords

ASJC Scopus subject areas

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