TY - JOUR
T1 - Comparison of continuous glucose monitoring in adolescents with type 1 diabetes
T2 - Ramadan versus non-Ramadan
AU - Kaplan, Walid
AU - Afandi, Bachar
AU - Al Hassani, Noura
AU - Hadi, Suha
AU - Zoubeidi, Taoufik
N1 - Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2017/12
Y1 - 2017/12
N2 - Aim To assess the impact of fasting on interstitial glucose (IG) in adolescents with type 1 DM (T1DM) by using continuous glucose monitoring (CGM). Method A minimum of 2.5 days CGM was done on adolescents with T1DM during fasting in Ramadan and in the month before or after Ramadan to compare the differences in mean IG, and in the durations of hypoglycemia (<70 mg/dL), hyperglycemia (200–299 mg/dL), and severe hyperglycemia (≥300 mg/dL). Results Fourteen adolescents were studied, age 15 ± 4 years, duration of diabetes 6 ± 4 years, and HbA1C 8.6 ± 1.1% (70.3 mmol/mol). There was no difference in the mean IG (190 ± 39 and 180 ± 37, p = 0.4), or in the durations of hypoglycemia (5.14 ± 5% and 7.03 ± 4.9%, p = 0.3), hyperglycemia (25.35 ± 11.3% and 24.24 ± 10.1% (P = 0.7)), and severe hyperglycemia (13.21 ± 13.4% and 10.96 ± 10.6%, P = 0.6), between Ramadan and, non-Ramadan, respectively. Conclusion Adolescents with T1DM have the same wide fluctuation in IG during fasting in Ramadan as they do outside Ramadan. Insulin regimen adjustment should be targeting both extremes of glucose abnormality.
AB - Aim To assess the impact of fasting on interstitial glucose (IG) in adolescents with type 1 DM (T1DM) by using continuous glucose monitoring (CGM). Method A minimum of 2.5 days CGM was done on adolescents with T1DM during fasting in Ramadan and in the month before or after Ramadan to compare the differences in mean IG, and in the durations of hypoglycemia (<70 mg/dL), hyperglycemia (200–299 mg/dL), and severe hyperglycemia (≥300 mg/dL). Results Fourteen adolescents were studied, age 15 ± 4 years, duration of diabetes 6 ± 4 years, and HbA1C 8.6 ± 1.1% (70.3 mmol/mol). There was no difference in the mean IG (190 ± 39 and 180 ± 37, p = 0.4), or in the durations of hypoglycemia (5.14 ± 5% and 7.03 ± 4.9%, p = 0.3), hyperglycemia (25.35 ± 11.3% and 24.24 ± 10.1% (P = 0.7)), and severe hyperglycemia (13.21 ± 13.4% and 10.96 ± 10.6%, P = 0.6), between Ramadan and, non-Ramadan, respectively. Conclusion Adolescents with T1DM have the same wide fluctuation in IG during fasting in Ramadan as they do outside Ramadan. Insulin regimen adjustment should be targeting both extremes of glucose abnormality.
KW - Adolescent
KW - CGM
KW - Fasting
KW - Ramadan
KW - Type 1
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U2 - 10.1016/j.diabres.2017.10.010
DO - 10.1016/j.diabres.2017.10.010
M3 - Article
C2 - 29061323
AN - SCOPUS:85032987412
SN - 0168-8227
VL - 134
SP - 178
EP - 182
JO - Diabetes Research and Clinical Practice
JF - Diabetes Research and Clinical Practice
ER -
