@article{240b835224fe4576b5a00e1583531efe,
title = "Comprehensive Mechanism of Gene Silencing and Its Role in Plant Growth and Development",
abstract = "Gene silencing is a negative feedback mechanism that regulates gene expression to define cell fate and also regulates metabolism and gene expression throughout the life of an organism. In plants, gene silencing occurs via transcriptional gene silencing (TGS) and post-transcriptional gene silencing (PTGS). TGS obscures transcription via the methylation of 5′ untranslated region (5′UTR), whereas PTGS causes the methylation of a coding region to result in transcript degradation. In this review, we summarized the history and molecular mechanisms of gene silencing and underlined its specific role in plant growth and crop production.",
keywords = "CRISPR/Cas9, RNAi, genomics imprinting, paramutation, post-transcriptional gene silencing, transcriptional gene silencing",
author = "El-Sappah, {Ahmed H.} and Kuan Yan and Qiulan Huang and Islam, {Md Monirul} and Quanzi Li and Yu Wang and Khan, {Muhammad Sarwar} and Xianming Zhao and Mir, {Reyazul Rouf} and Jia Li and El-Tarabily, {Khaled A.} and Manzar Abbas",
note = "Funding Information: This study was supported by the Sichuan Provincial Department of Science and Technology Project (Grant No. 18ZDYF0293), the Key Laboratory of Sichuan Province for Refining Sichuan Tea, and the Sichuan Province Tea Industry Group Co., Ltd. Funding Information: We are very grateful to the kind administration of Yibin University, Yibin, China for providing us such a prestigious and well-equipped platform for research and development. We are also grateful to the kind administration of the Ministry of Science and Technology of Sichuan province, China. Finally, KE-T would like to thank the library at Murdoch University-Australia for the valuable online resources and comprehensive databases. Funding. This study was supported by the Sichuan Provincial Department of Science and Technology Project (Grant No. 18ZDYF0293), the Key Laboratory of Sichuan Province for Refining Sichuan Tea, and the Sichuan Province Tea Industry Group Co., Ltd. Publisher Copyright: {\textcopyright} Copyright {\textcopyright} 2021 El-Sappah, Yan, Huang, Islam, Li, Wang, Khan, Zhao, Mir, Li, El-Tarabily and Abbas.",
year = "2021",
month = sep,
day = "7",
doi = "10.3389/fpls.2021.705249",
language = "English",
volume = "12",
journal = "Frontiers in Plant Science",
issn = "1664-462X",
publisher = "Frontiers Media S. A.",
}