TY - JOUR
T1 - Curcumin, the active substance of turmeric
T2 - its effects on health and ways to improve its bioavailability
AU - Abd El-Hack, Mohamed E.
AU - El-Saadony, Mohamed T.
AU - Swelum, Ayman A.
AU - Arif, Muhammad
AU - Abo Ghanima, Mahmoud M.
AU - Shukry, Mustafa
AU - Noreldin, Ahmed
AU - Taha, Ayman E.
AU - El-Tarabily, Khaled A.
N1 - Funding Information:
The authors are grateful for support from their universities and institutes. K.A. El‐Tarabily would like to thank the library at Murdoch University, Australia, for the provision of valuable online resources and comprehensive databases. This work was funded by the Abu Dhabi Research Award (AARE2019) for Research Excellence, Department of Education and Knowledge (ADEK‐007; Grant #: 21S105) United Arab Emirates to Prof. Khaled A. El‐Tarabily.
Funding Information:
The authors are grateful for support from their universities and institutes. K.A. El-Tarabily would like to thank the library at Murdoch University, Australia, for the provision of valuable online resources and comprehensive databases. This work was funded by the Abu Dhabi Research Award (AARE2019) for Research Excellence, Department of Education and Knowledge (ADEK-007; Grant #: 21S105) United Arab Emirates to Prof. Khaled A. El-Tarabily.
Publisher Copyright:
© 2021 Society of Chemical Industry.
PY - 2021/11
Y1 - 2021/11
N2 - Turmeric (Curcuma longa L.) is a spice utilized widely in India, China, and Southeast Asia as an aromatic stimulant, a food preservative, and coloring material. The commonly used names of turmeric are castor saffron, turmeric, and saffron root. Turmeric is a yellow–orange polyphenolic natural substance derived from C. longa rhizomes. It has been used to treat common inflammatory diseases, tumors, biliary diseases, anorexia, cough, topical wounds, diabetic injuries, liver disorders, rheumatism, and sinusitis. Extensive studies on the biological properties and pharmacological consequences of turmeric extracts have been conducted in recent years. Curcumin, the primary yellow biocomponent of turmeric, has anti-inflammatory, antioxidant, anticarcinogenic, antidiabetic, antibacterial, antiprotozoal, antiviral, antifibrotic, immunomodulatory, and antifungal properties. Defense assessment tests showed that curcumin is tolerated well at high doses, without adverse effects. Thus, curcumin is a highly active biological material with the potential to treat different diseases in modern medicine. This review article focuses on curcumin's biological characteristics. The most popular methods for curcumin encapsulation are also discussed. Several effective techniques and approaches have been proposed for curcuminoid capsulation, including nanocomplexing, gelation, complex coacervation, electrospraying, and solvent-free pH-driven encapsulation. This review also highlights curcumin's chemical properties, allowing the readers to expand their perspectives on its use in the development of functional products with health-promoting properties.
AB - Turmeric (Curcuma longa L.) is a spice utilized widely in India, China, and Southeast Asia as an aromatic stimulant, a food preservative, and coloring material. The commonly used names of turmeric are castor saffron, turmeric, and saffron root. Turmeric is a yellow–orange polyphenolic natural substance derived from C. longa rhizomes. It has been used to treat common inflammatory diseases, tumors, biliary diseases, anorexia, cough, topical wounds, diabetic injuries, liver disorders, rheumatism, and sinusitis. Extensive studies on the biological properties and pharmacological consequences of turmeric extracts have been conducted in recent years. Curcumin, the primary yellow biocomponent of turmeric, has anti-inflammatory, antioxidant, anticarcinogenic, antidiabetic, antibacterial, antiprotozoal, antiviral, antifibrotic, immunomodulatory, and antifungal properties. Defense assessment tests showed that curcumin is tolerated well at high doses, without adverse effects. Thus, curcumin is a highly active biological material with the potential to treat different diseases in modern medicine. This review article focuses on curcumin's biological characteristics. The most popular methods for curcumin encapsulation are also discussed. Several effective techniques and approaches have been proposed for curcuminoid capsulation, including nanocomplexing, gelation, complex coacervation, electrospraying, and solvent-free pH-driven encapsulation. This review also highlights curcumin's chemical properties, allowing the readers to expand their perspectives on its use in the development of functional products with health-promoting properties.
KW - bioavailability
KW - biological activity
KW - curcumin
KW - electrospraying
KW - gelation
KW - nanocomplexation
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UR - http://www.scopus.com/inward/citedby.url?scp=85110020446&partnerID=8YFLogxK
U2 - 10.1002/jsfa.11372
DO - 10.1002/jsfa.11372
M3 - Review article
C2 - 34143894
AN - SCOPUS:85110020446
SN - 0022-5142
VL - 101
SP - 5747
EP - 5762
JO - Journal of the Science of Food and Agriculture
JF - Journal of the Science of Food and Agriculture
IS - 14
ER -