Development and characterization of novel biopolymer derived from abelmoschus esculentus l. Extract and its antidiabetic potential

Abd Elmoneim O. Elkhalifa, Eyad Al-Shammari, Mohd Adnan, Jerold C. Alcantara, Khalid Mehmood, Nagat Elzein Eltoum, Amir Mahgoub Awadelkareem, Mushtaq Ahmad Khan, Syed Amir Ashraf

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


Abelmoschus esculentus (Okra) is an important vegetable crop, widely cultivated around the world due to its high nutritional significance along with several health benefits. Different parts of okra including its mucilage have been currently studied for its role in various therapeutic applications. Therefore, we aimed to develop and characterize the okra mucilage biopolymer (OMB) for its physicochemical properties as well as to evaluate its in vitro antidiabetic activity. The characterization of OMB using Fourier-transform infrared spectroscopy (FT-IR) revealed that okra mucilage containing polysaccharides lies in the bandwidth of 3279 and 1030 cm−1, which constitutes the fingerprint region of the spectrum. In addition, physicochemical parameters such as percentage yield, percentage solubility, and swelling index were found to be 2.66%, 96.9%, and 5, respectively. A mineral analysis of newly developed biopolymers showed a substantial amount of calcium (412 mg/100 g), potassium (418 mg/100 g), phosphorus (60 mg/100 g), iron (47 mg/100 g), zinc (16 mg/100 g), and sodium (9 mg/100 g). The significant antidiabetic potential of OMB was demonstrated using α-amylase and α-glucosidase enzyme inhibitory assay. Further investigations are required to explore the newly developed biopolymer for its toxicity, efficacy, and its possible utilization in food, nutraceutical, as well as pharmaceutical industries.

Original languageEnglish
Article number3609
Issue number12
Publication statusPublished - Jun 2 2021


  • Antidiabetic activity
  • Biopolymer
  • Nutraceuticals
  • Okra mucilage
  • Okra polysaccharides
  • α-amylase activity
  • α-glucosidase activity

ASJC Scopus subject areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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