DIAGNOSTISCHE BEDEUTUNG DES TUMORMARKERS CA 19-9 BEIM PANKREASKARZINOM

Translated title of the contribution: Diagnostic significance of the tumour marker CA 19-9 in carcinoma of the pancreas

F. Safi, M. Buchler, B. Schenkluhn, H. G. Beger

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

The diagnostic value of the tumour-associated antigen CA 19-9 was tested in 309 patients, 156 with malignancies (39 carcinoma of the pancreas, 117 extrapancreatic malignant tumour) and 153 patients with non-malignant disease (54 chronic pancreatitis, 25 acute pancreatitis, 74 general surgical disease). Levels above the normal range of 6-37 U/ml were obtained in 95% of patients with carcinoma of the pancreas (mean value 528 U/ml), in 31% of patients with gastric carcinoma and 16% with colorectal carcinoma (mean 8 U/ml). Results of the pre-operative determination of CA 19-9 indicated for carcinoma of the pancreas a sensitivity of 95%, a specificity of 87% and an overall accuracy of 88%. Pre-operatively elevated CA 19-9 concentrations in patients with carcinoma of the pancreas fell to normal after curative resection of the neoplasm. After palliative opertion or in inoperable carcinoma CA 19-9 serum concentrations were never less than 37 U/ml.

Translated title of the contributionDiagnostic significance of the tumour marker CA 19-9 in carcinoma of the pancreas
Original languageGerman
Pages (from-to)1869-1873
Number of pages5
JournalDeutsche Medizinische Wochenschrift
Volume109
Issue number49
DOIs
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Medicine(all)

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