Digital interventions for smoking abstinence: a systematic review and meta-analysis of randomized control trials

Sohrab Amiri, Moien A.B. Khan

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)


Objectives: Technological advancements have improved patients’ health and clinical care through digital interventions. This study investigated the effects of digital interventions on smoking abstinence. Methods: PubMed, the Cochrane Library, and Scopus were systematically searched from inception until December 2021. Meta-analysis was carried out using a random-effects model. The degree of heterogeneity, quality, and publication bias of the selected studies was further evaluated. Results: A total of 43 randomized control trial studies were eligible for this study. 38,814 participants from 18 countries were included in the analysis. Digital interventions on seven-day point prevalence abstinence (1 month) showed increased smoking abstinence. The odds ratio was 2.02 and confidence interval (CI) was 1.67–2.43; p < 0.001; I 2 = 55.1%). The result for a 30-day point prevalence abstinence (1 month) was 1.63 (CI 1.09–2.46; p = 0.018; I 2 = 0%). Digital intervention also had a significant effect on continuous abstinence (odds ratio = 1.68; CI 1.29–2.18; p < 0.001; I 2 = 70.1%) and prolonged abstinence (odds ratio = 1.60; CI 1.19–2.15; p = 0.002; I 2 = 53.6%). There was evidence of heterogeneity and publication bias. Conclusions: Digital interventions led to increased smoking abstinence and can be a valuable tool in smoking cessation. Further research is required to evaluate the long-term impact of digital interventions on outcomes related to smoking cessation.

Original languageEnglish
Pages (from-to)4-29
Number of pages26
JournalJournal of Addictive Diseases
Issue number1
Publication statusPublished - 2023


  • Smoking cessation
  • abstinence
  • digital intervention
  • meta-analysis
  • systematic review
  • tobacco

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Clinical Psychology
  • Psychiatry and Mental health


Dive into the research topics of 'Digital interventions for smoking abstinence: a systematic review and meta-analysis of randomized control trials'. Together they form a unique fingerprint.

Cite this