DNA Nucleotides Detection via C2N Sensor: First-Principles Modeling

Asma Wasfi, Falah Awwad

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Due to the outstanding electrical and physical properties of two-dimensional Nitrogenated Holey Graphene (C2N) based sensors, they have become increasingly important. In comparison to other solid-state sensors, C2N-based sensors are very sensitive, stable, and responsive. The conductivity of C2N changes when exposed to a wide range of organic and inorganic substances. Different target molecules are being detected using this change in electrical conductivity as a detection signal. With first-principles transport simulation, a sensor device built from Nitrogenated Holey Graphene (C2N) sensor is designed for DNA nucleotides detection. The transverse currents of this sensor can be used to discriminate between the four DNA nucleotides. A C2N-based sensor is simulated in this article using Quantumwise Atomistix Toolkit (ATK), a simulator for nanoscale semiconductor devices. Calculations have been made to determine how the work function, density of state, and electric current vary when target molecules are present. To increase the sensor's selectivity and accuracy, the current has been considered as a detecting mechanism. When target molecules are present, the change in work function and the electric current can both be used as detection signals.

Original languageEnglish
Title of host publication2023 IEEE Sensors Applications Symposium, SAS 2023 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9798350323078
Publication statusPublished - 2023
Event18th IEEE Sensors Applications Symposium, SAS 2023 - Ottawa, Canada
Duration: Jul 18 2023Jul 20 2023

Publication series

Name2023 IEEE Sensors Applications Symposium, SAS 2023 - Proceedings


Conference18th IEEE Sensors Applications Symposium, SAS 2023


  • CN
  • First-principles
  • Nitrogenated Holey Graphene
  • Non-equilibrium Green's function (NEGF)
  • Nucleotides Sensor

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Instrumentation


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