TY - JOUR
T1 - Dynamics of tumor-immune system with random noise
AU - Rihan, Fathalla A.
AU - Rajivganthi, Chinnathambi
N1 - Funding Information:
Funding: This research was funded by UAE University, fund # 12S005-UPAR 2020.
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/11/1
Y1 - 2021/11/1
N2 - With deterministic differential equations, we can understand the dynamics of tumor-immune interactions. Cancer-immune interactions can, however, be greatly disrupted by random factors, such as physiological rhythms, environmental factors, and cell-to-cell communication. The present study introduces a stochastic differential model in infectious diseases and immunology of the dynamics of a tumorimmune system with random noise. Stationary ergodic distribution of positive solutions to the system is investigated in which the solution fluctuates around the equilibrium of the deterministic case and causes the disease to persist stochastically. In some conditions, it may be possible to attain infection-free status, where diseases die out exponentially with a probability of one. Some numerical simulations are conducted with the Euler–Maruyama scheme in order to verify the results. White noise intensity is a key factor in treating infectious diseases.
AB - With deterministic differential equations, we can understand the dynamics of tumor-immune interactions. Cancer-immune interactions can, however, be greatly disrupted by random factors, such as physiological rhythms, environmental factors, and cell-to-cell communication. The present study introduces a stochastic differential model in infectious diseases and immunology of the dynamics of a tumorimmune system with random noise. Stationary ergodic distribution of positive solutions to the system is investigated in which the solution fluctuates around the equilibrium of the deterministic case and causes the disease to persist stochastically. In some conditions, it may be possible to attain infection-free status, where diseases die out exponentially with a probability of one. Some numerical simulations are conducted with the Euler–Maruyama scheme in order to verify the results. White noise intensity is a key factor in treating infectious diseases.
KW - Cancer-immune system
KW - Infectious diseases
KW - Random noise
KW - Steady states
KW - Stochastic differential equations
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U2 - 10.3390/math9212707
DO - 10.3390/math9212707
M3 - Article
AN - SCOPUS:85118245957
SN - 2227-7390
VL - 9
JO - Mathematics
JF - Mathematics
IS - 21
M1 - 2707
ER -