Early diagnosis of bilateral retinoblastoma reduces death and blindness

D. J. Derkinderen, J. W. Koten, L. K.J. Van Romunde, N. J.D. Nagelkerke, K. E.W.P. Tan, F. A. Beemer, W. Den Otter

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


The influence of early diagnosis on sight and survival was studied in 130 patients with bilateral retinoblastoma. Nineteen patients died of this condition. Statistical analysis predicted that 12 of these 19 early deaths could have been prevented if doctors' delay had been less than I week. Consequently, a reduction of 65% in mortality is possible. Similarly, statistical analysis also predicted that the number of patients with resulting blindness could be reduced by 40%. Central registration and monitoring of retinoblastoma families would greatly improve early diagnosis.

Original languageEnglish
Pages (from-to)35-39
Number of pages5
JournalInternational Journal of Cancer
Issue number1
Publication statusPublished - Jul 15 1989
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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