Early diagnosis of bilateral retinoblastoma reduces death and blindness

D. J. Derkinderen; J. W. Koten; L. K.J. Van Romunde; N. J.D. Nagelkerke; K. E.W.P. Tan; F. A. Beemer; W. Den Otter

doi:10.1002/ijc.2910440107

Early diagnosis of bilateral retinoblastoma reduces death and blindness

D. J. Derkinderen, J. W. Koten, L. K.J. Van Romunde, N. J.D. Nagelkerke, K. E.W.P. Tan, F. A. Beemer, W. Den Otter

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

The influence of early diagnosis on sight and survival was studied in 130 patients with bilateral retinoblastoma. Nineteen patients died of this condition. Statistical analysis predicted that 12 of these 19 early deaths could have been prevented if doctors' delay had been less than I week. Consequently, a reduction of 65% in mortality is possible. Similarly, statistical analysis also predicted that the number of patients with resulting blindness could be reduced by 40%. Central registration and monitoring of retinoblastoma families would greatly improve early diagnosis.

Original language	English
Pages (from-to)	35-39
Number of pages	5
Journal	International Journal of Cancer
Volume	44
Issue number	1
DOIs	https://doi.org/10.1002/ijc.2910440107
Publication status	Published - Jul 15 1989
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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AU - Nagelkerke, N. J.D.

AU - Tan, K. E.W.P.

AU - Beemer, F. A.

AU - Den Otter, W.

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Early diagnosis of bilateral retinoblastoma reduces death and blindness

Abstract

ASJC Scopus subject areas

UN SDGs

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