Effect of bovine pancreatic polypeptide on basal pancreatic and biliary outputs in man

G. R. Greenberg; R. F. McCloy; V. S. Chadwick; T. E. Adrian; J. H. Baron; S. R. Bloom

doi:10.1007/BF01297231

Effect of bovine pancreatic polypeptide on basal pancreatic and biliary outputs in man

G. R. Greenberg, R. F. McCloy, V. S. Chadwick, T. E. Adrian, J. H. Baron, S. R. Bloom

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Abstract

Basal pancreatic and biliary outputs were examined in seven healthy volunteers during intravenous infusion of bovine pancreatic polypeptide (BPP) at a mean dose of 320 pmoll kg/hr. BPP significantly (P<0.02) inhibited outputs of trypsin and bilirubin, without affecting bicarbonate. These studies suggest the possibility that pancreatic polypeptide may have a role in the regulation of biliary and pancreatic enzyme secretion in man.

Original language	English
Pages (from-to)	11-14
Number of pages	4
Journal	Digestive Diseases and Sciences
Volume	24
Issue number	1
DOIs	https://doi.org/10.1007/BF01297231
Publication status	Published - Jan 1979
Externally published	Yes

ASJC Scopus subject areas

Physiology
Gastroenterology

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10.1007/BF01297231

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AU - McCloy, R. F.

AU - Chadwick, V. S.

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AU - Baron, J. H.

AU - Bloom, S. R.

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AB - Basal pancreatic and biliary outputs were examined in seven healthy volunteers during intravenous infusion of bovine pancreatic polypeptide (BPP) at a mean dose of 320 pmoll kg/hr. BPP significantly (P<0.02) inhibited outputs of trypsin and bilirubin, without affecting bicarbonate. These studies suggest the possibility that pancreatic polypeptide may have a role in the regulation of biliary and pancreatic enzyme secretion in man.

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Effect of bovine pancreatic polypeptide on basal pancreatic and biliary outputs in man

Abstract

ASJC Scopus subject areas

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