Effect of bovine pancreatic polypeptide on basal pancreatic and biliary outputs in man

G. R. Greenberg, R. F. McCloy, V. S. Chadwick, T. E. Adrian, J. H. Baron, S. R. Bloom

Research output: Contribution to journalArticlepeer-review

73 Citations (Scopus)

Abstract

Basal pancreatic and biliary outputs were examined in seven healthy volunteers during intravenous infusion of bovine pancreatic polypeptide (BPP) at a mean dose of 320 pmoll kg/hr. BPP significantly (P<0.02) inhibited outputs of trypsin and bilirubin, without affecting bicarbonate. These studies suggest the possibility that pancreatic polypeptide may have a role in the regulation of biliary and pancreatic enzyme secretion in man.

Original languageEnglish
Pages (from-to)11-14
Number of pages4
JournalDigestive Diseases and Sciences
Volume24
Issue number1
DOIs
Publication statusPublished - Jan 1979
Externally publishedYes

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology

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