Effect of bovine pancreatic polypeptide on basal pancreatic and biliary outputs in man

G. R. Greenberg; R. F. McCloy; V. S. Chadwick; T. E. Adrian; J. H. Baron; S. R. Bloom

doi:10.1007/BF01297231

Effect of bovine pancreatic polypeptide on basal pancreatic and biliary outputs in man

G. R. Greenberg
, R. F. McCloy
, V. S. Chadwick
, T. E. Adrian
, J. H. Baron
, S. R. Bloom

Research output: Contribution to journal › Article › peer-review

76 Citations (Scopus)

Abstract

Basal pancreatic and biliary outputs were examined in seven healthy volunteers during intravenous infusion of bovine pancreatic polypeptide (BPP) at a mean dose of 320 pmoll kg/hr. BPP significantly (P<0.02) inhibited outputs of trypsin and bilirubin, without affecting bicarbonate. These studies suggest the possibility that pancreatic polypeptide may have a role in the regulation of biliary and pancreatic enzyme secretion in man.

Original language	English
Pages (from-to)	11-14
Number of pages	4
Journal	Digestive Diseases and Sciences
Volume	24
Issue number	1
DOIs	https://doi.org/10.1007/BF01297231
Publication status	Published - Jan 1979
Externally published	Yes

ASJC Scopus subject areas

Physiology
Gastroenterology

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10.1007/BF01297231

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title = "Effect of bovine pancreatic polypeptide on basal pancreatic and biliary outputs in man",

abstract = "Basal pancreatic and biliary outputs were examined in seven healthy volunteers during intravenous infusion of bovine pancreatic polypeptide (BPP) at a mean dose of 320 pmoll kg/hr. BPP significantly (P<0.02) inhibited outputs of trypsin and bilirubin, without affecting bicarbonate. These studies suggest the possibility that pancreatic polypeptide may have a role in the regulation of biliary and pancreatic enzyme secretion in man.",

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year = "1979",

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AU - Greenberg, G. R.

AU - McCloy, R. F.

AU - Chadwick, V. S.

AU - Adrian, T. E.

AU - Baron, J. H.

AU - Bloom, S. R.

PY - 1979/1

Y1 - 1979/1

N2 - Basal pancreatic and biliary outputs were examined in seven healthy volunteers during intravenous infusion of bovine pancreatic polypeptide (BPP) at a mean dose of 320 pmoll kg/hr. BPP significantly (P<0.02) inhibited outputs of trypsin and bilirubin, without affecting bicarbonate. These studies suggest the possibility that pancreatic polypeptide may have a role in the regulation of biliary and pancreatic enzyme secretion in man.

AB - Basal pancreatic and biliary outputs were examined in seven healthy volunteers during intravenous infusion of bovine pancreatic polypeptide (BPP) at a mean dose of 320 pmoll kg/hr. BPP significantly (P<0.02) inhibited outputs of trypsin and bilirubin, without affecting bicarbonate. These studies suggest the possibility that pancreatic polypeptide may have a role in the regulation of biliary and pancreatic enzyme secretion in man.

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Effect of bovine pancreatic polypeptide on basal pancreatic and biliary outputs in man

Abstract

ASJC Scopus subject areas

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