TY - GEN
T1 - Effect of manifold design on flow distribution in multichanneled microfluidic devices
AU - Mathew, B.
AU - John, T. J.
AU - Hegab, H.
PY - 2009
Y1 - 2009
N2 - The effect of channel width and channel spacing on the flow distribution in a microfluidic device with U-type manifolds is numerically analyzed in this paper. Analysis is performed for flow rates between 1 ml/min and 60 ml/min. Flow distribution in a microfluidic device with three different microchannel widths are studied: 50 μm, 100 μm, and 200 μm. Reduction in the microchannel width reduced the non-uniformity in flow rate. Moreover, the flow malidistribution increased with increase in flow rate. The RMS value of the deviation of flow rate per channel reduced from 3 ml/min to 0.3 ml/min with reduction in channel width for a total flow rate of 60 ml/min. The effect of channel spacing on flow distribution was investigated for three channel spacing of 300 μm, 100 μm, and 50 μm. Reduction in channel spacing increased nonuniformity of flow distribution. The RMS value of the deviation of flow rate per flow rate reduced from 1 ml/min to 0.6 ml/min with increase in channel spacing for the greatest flow rate. From the particular studies examined in this paper it is found channel width has a stronger influence on flow distribution than channel spacing. Moreover, proper selection of channel width and channel spacing can uniformly distribute flow.
AB - The effect of channel width and channel spacing on the flow distribution in a microfluidic device with U-type manifolds is numerically analyzed in this paper. Analysis is performed for flow rates between 1 ml/min and 60 ml/min. Flow distribution in a microfluidic device with three different microchannel widths are studied: 50 μm, 100 μm, and 200 μm. Reduction in the microchannel width reduced the non-uniformity in flow rate. Moreover, the flow malidistribution increased with increase in flow rate. The RMS value of the deviation of flow rate per channel reduced from 3 ml/min to 0.3 ml/min with reduction in channel width for a total flow rate of 60 ml/min. The effect of channel spacing on flow distribution was investigated for three channel spacing of 300 μm, 100 μm, and 50 μm. Reduction in channel spacing increased nonuniformity of flow distribution. The RMS value of the deviation of flow rate per flow rate reduced from 1 ml/min to 0.6 ml/min with increase in channel spacing for the greatest flow rate. From the particular studies examined in this paper it is found channel width has a stronger influence on flow distribution than channel spacing. Moreover, proper selection of channel width and channel spacing can uniformly distribute flow.
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U2 - 10.1115/FEDSM2009-78531
DO - 10.1115/FEDSM2009-78531
M3 - Conference contribution
AN - SCOPUS:77953813830
SN - 9780791843734
T3 - Proceedings of the ASME Fluids Engineering Division Summer Conference 2009, FEDSM2009
SP - 543
EP - 548
BT - Proceedings of the ASME Fluids Engineering Division Summer Conference 2009, FEDSM2009
T2 - 2009 ASME Fluids Engineering Division Summer Conference, FEDSM2009
Y2 - 2 August 2009 through 6 August 2009
ER -