Abstract
This study examined the effect of 0.05 mg norgestrel + 0.01 ethinyl estradiol (NEE) Kg · body wt-1 on body weight, random blood glucose, glycosylated hemoglobin, and plasma insulin levels in streptozotocin-induced diabetic rats. Weight loss, blood glucose, glycosylated hemoglobin, and plasma insulin values of rats treated with NEE before and after the onset of diabetes were not significantly different from that of untreated diabetic rats. In conclusion, oral administration of these contraceptive steroid hormones does not significantly alter the metabolic parameters of diabetic rats.
Original language | English |
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Pages (from-to) | 327-329 |
Number of pages | 3 |
Journal | Contraception |
Volume | 62 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2000 |
Keywords
- Diabetes mellitus
- Glycosylated hemoglobin
- Insulin
- Metabolic parameters
- Oral contraceptive hormones
- Radioimmunoassay
- Rat
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology