Effect of oral contraceptive steroid hormones on metabolic parameters of streptozotocin-induced diabetic rat

E. Adeghate

doi:10.1016/S0010-7824(00)00180-3

Effect of oral contraceptive steroid hormones on metabolic parameters of streptozotocin-induced diabetic rat

E. Adeghate

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

This study examined the effect of 0.05 mg norgestrel + 0.01 ethinyl estradiol (NEE) Kg · body wt^-1 on body weight, random blood glucose, glycosylated hemoglobin, and plasma insulin levels in streptozotocin-induced diabetic rats. Weight loss, blood glucose, glycosylated hemoglobin, and plasma insulin values of rats treated with NEE before and after the onset of diabetes were not significantly different from that of untreated diabetic rats. In conclusion, oral administration of these contraceptive steroid hormones does not significantly alter the metabolic parameters of diabetic rats.

Original language	English
Pages (from-to)	327-329
Number of pages	3
Journal	Contraception
Volume	62
Issue number	6
DOIs	https://doi.org/10.1016/S0010-7824(00)00180-3
Publication status	Published - 2000

Keywords

Diabetes mellitus
Glycosylated hemoglobin
Insulin
Metabolic parameters
Oral contraceptive hormones
Radioimmunoassay
Rat

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynaecology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0010-7824(00)00180-3

Cite this

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title = "Effect of oral contraceptive steroid hormones on metabolic parameters of streptozotocin-induced diabetic rat",

abstract = "This study examined the effect of 0.05 mg norgestrel + 0.01 ethinyl estradiol (NEE) Kg · body wt-1 on body weight, random blood glucose, glycosylated hemoglobin, and plasma insulin levels in streptozotocin-induced diabetic rats. Weight loss, blood glucose, glycosylated hemoglobin, and plasma insulin values of rats treated with NEE before and after the onset of diabetes were not significantly different from that of untreated diabetic rats. In conclusion, oral administration of these contraceptive steroid hormones does not significantly alter the metabolic parameters of diabetic rats.",

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AB - This study examined the effect of 0.05 mg norgestrel + 0.01 ethinyl estradiol (NEE) Kg · body wt-1 on body weight, random blood glucose, glycosylated hemoglobin, and plasma insulin levels in streptozotocin-induced diabetic rats. Weight loss, blood glucose, glycosylated hemoglobin, and plasma insulin values of rats treated with NEE before and after the onset of diabetes were not significantly different from that of untreated diabetic rats. In conclusion, oral administration of these contraceptive steroid hormones does not significantly alter the metabolic parameters of diabetic rats.

KW - Diabetes mellitus

KW - Glycosylated hemoglobin

KW - Insulin

KW - Metabolic parameters

KW - Oral contraceptive hormones

KW - Radioimmunoassay

KW - Rat

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Effect of oral contraceptive steroid hormones on metabolic parameters of streptozotocin-induced diabetic rat

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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