Effect of selenium supplementation on blood status and milk, urine, and fecal excretion in pregnant and lactating camel

Ten pregnant female camels divided into two groups received, after a 2-week adaptation period, an oral selenium (Se) supplementation (0 and 2 mg, respectively) under sodium selenite form for 6 months from the three last months of gestation up to the three first months of lactation. Feed intake was assessed daily. Blood samples and body weight were taken on a biweekly basis, both in dams and their camel calves after parturition. Feces and urine samples were collected monthly and milk on a biweekly basis. The Se concentration in serum increased significantly in the supplemented group and was threefold higher than the concentration compared to the control group, respectively, 305.9±103.3 and 109.3±33.1 ng/mL. The selenium concentration increased in similar proportion in milk (86.4±39.1 ng/mL in the control group vs 167.1±97.3 ng/mL in treated group), in urine, and feces. The gluthathione peroxidase (GSH-Px) activity varied between 18.1±8.7 IU/g hemoglobin (Hb) in control group and 47.5±25.6 IU/g Hb in treated group but decreased after parturition in both groups. Vitamin E did not change significantly and was, on average, 1.17±0.72 and 1.14±0.89 ng/mL in the control and treated groups, respectively. Significant correlations were reported between serum Se, milk Se, GSH-Px, and fecal and urinary excretion or concentration. Blood values in camel calves were similar to those of the dams. The results seemed to confirm the sensitivity of camel to Se supplementation with an important increase of selenium in serum and milk.