TY - JOUR
T1 - Effect of single dose of omeprazole on the gastrointestinal peptide response to food
AU - Allen, J. M.
AU - Adrian, T. E.
AU - Webster, J.
AU - Howe, A.
AU - Bloom, S. R.
PY - 1984
Y1 - 1984
N2 - The gastrointestinal peptide response to food was assessed in 6 healthy subjects following oral administration of 40 mg omeprazole. There was a small but statistically significant increase in basal plasma gastrin six hours after the dose of omeprazole, but the post-prandial plasma gastrin was not significantly increased. There was no significant effect on basal or post-prandial levels of somatostatin, insulin, pancreatic glucagon, enteroglucagon, gastric inhibitory polypeptide, pancreatic polypeptide, motilin, neurotensin, cholecystokinin, secretin, vasoactive intestinal peptide and gastrin-releasing peptide or blood glucose concentration.
AB - The gastrointestinal peptide response to food was assessed in 6 healthy subjects following oral administration of 40 mg omeprazole. There was a small but statistically significant increase in basal plasma gastrin six hours after the dose of omeprazole, but the post-prandial plasma gastrin was not significantly increased. There was no significant effect on basal or post-prandial levels of somatostatin, insulin, pancreatic glucagon, enteroglucagon, gastric inhibitory polypeptide, pancreatic polypeptide, motilin, neurotensin, cholecystokinin, secretin, vasoactive intestinal peptide and gastrin-releasing peptide or blood glucose concentration.
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M3 - Article
C2 - 6365714
AN - SCOPUS:0021269188
SN - 0172-6390
VL - 31
SP - 44
EP - 46
JO - Hepato-Gastroenterology
JF - Hepato-Gastroenterology
IS - 1
ER -