TY - JOUR
T1 - Electrochemiluminescence of Ru(bpy)32+/Oxamic Hydrazide and its Application for Selective Detection of 4-Nitrobenzaldehyde
AU - Yuan, Fan
AU - Halawa, Mohamed Ibrahim
AU - Ma, Xiangui
AU - Abdussalam, Abubakar
AU - Lou, Baohua
AU - Xu, Guobao
N1 - Publisher Copyright:
© 2020 Wiley-VCH GmbH
PY - 2020/10/16
Y1 - 2020/10/16
N2 - Oxamic hydrazide (OHA) was utilized as an efficient coreactant of Ru(bpy)32+ for the first time, which can dramatically increase the electrochemiluminescence (ECL) intensity of Ru(bpy)32+ on glassy carbon electrode (GCE). 4-nitrobenzaldehyde (4-NBA), a nitroaromatic compound, has mutagenic and carcinogenic toxicity on humans′ genome and causes a serious impact on the environment. Hence, the detection of its level in biological and environmental samples is of great significance. Interestingly, 4-NBA was found to induce a dramatic quenching for the ECL intensity of the developed Ru(bpy)32+/OHA system owing to the formation of hydrazone product through the nucleophilic addition reaction with OHA. Under optimal conditions, the ECL decreasing value of Ru(bpy)32+/OHA in the presence of 4-NBA is linear in the range of 20 μM to 800 μM with a limit of detection (LOD) of 1.09 μM (signal-to-noise 3 : 1). Finally, this strategy enabled the detection of 4-NBA in tap water with satisfactory recoveries from 97.84 % to 103.56 %.
AB - Oxamic hydrazide (OHA) was utilized as an efficient coreactant of Ru(bpy)32+ for the first time, which can dramatically increase the electrochemiluminescence (ECL) intensity of Ru(bpy)32+ on glassy carbon electrode (GCE). 4-nitrobenzaldehyde (4-NBA), a nitroaromatic compound, has mutagenic and carcinogenic toxicity on humans′ genome and causes a serious impact on the environment. Hence, the detection of its level in biological and environmental samples is of great significance. Interestingly, 4-NBA was found to induce a dramatic quenching for the ECL intensity of the developed Ru(bpy)32+/OHA system owing to the formation of hydrazone product through the nucleophilic addition reaction with OHA. Under optimal conditions, the ECL decreasing value of Ru(bpy)32+/OHA in the presence of 4-NBA is linear in the range of 20 μM to 800 μM with a limit of detection (LOD) of 1.09 μM (signal-to-noise 3 : 1). Finally, this strategy enabled the detection of 4-NBA in tap water with satisfactory recoveries from 97.84 % to 103.56 %.
KW - Electrochemiluminescence
KW - Hydrazone
KW - Nucleophilic addition
KW - Ru(bpy)
UR - http://www.scopus.com/inward/record.url?scp=85094216429&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85094216429&partnerID=8YFLogxK
U2 - 10.1002/celc.202001140
DO - 10.1002/celc.202001140
M3 - Article
AN - SCOPUS:85094216429
SN - 2196-0216
VL - 7
SP - 4239
EP - 4244
JO - ChemElectroChem
JF - ChemElectroChem
IS - 20
ER -