Engineering glucosinolates in plants: Current knowledge and potential uses

Venkidasamy Baskar; Mayank Anand Gururani; Jae Woong Yu; Se Won Park

doi:10.1007/s12010-012-9890-6

Engineering glucosinolates in plants: Current knowledge and potential uses

Venkidasamy Baskar, Mayank Anand Gururani, Jae Woong Yu, Se Won Park

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

Glucosinolates (GSL) and their derivatives are well known for the characteristic roles they play in plant defense as signaling molecules and as bioactive compounds for human health. More than 130 GSLs have been reported so far, and most of them belong to the Brassicaceae family. Several enzymes and transcription factors involved in the GSL biosynthesis have been studied in the model plant, Arabidopsis, and in a few other Brassica crop species. Recent studies in GSL research have defined the regulation, distribution, and degradation of GSL biosynthetic pathways; however, the underlying mechanism behind transportation of GSLs in plants is still largely unknown. This review highlights the recent advances in the metabolic engineering of GSLs in plants and discusses their potential applications.

Original language	English
Pages (from-to)	1694-1717
Number of pages	24
Journal	Applied Biochemistry and Biotechnology
Volume	168
Issue number	6
DOIs	https://doi.org/10.1007/s12010-012-9890-6
Publication status	Published - Nov 2012
Externally published	Yes

Keywords

Brassicaceae
Glucosinolate
Myrosinase
Transgenic

ASJC Scopus subject areas

Biotechnology
Bioengineering
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology

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10.1007/s12010-012-9890-6

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abstract = "Glucosinolates (GSL) and their derivatives are well known for the characteristic roles they play in plant defense as signaling molecules and as bioactive compounds for human health. More than 130 GSLs have been reported so far, and most of them belong to the Brassicaceae family. Several enzymes and transcription factors involved in the GSL biosynthesis have been studied in the model plant, Arabidopsis, and in a few other Brassica crop species. Recent studies in GSL research have defined the regulation, distribution, and degradation of GSL biosynthetic pathways; however, the underlying mechanism behind transportation of GSLs in plants is still largely unknown. This review highlights the recent advances in the metabolic engineering of GSLs in plants and discusses their potential applications.",

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AU - Gururani, Mayank Anand

AU - Yu, Jae Woong

AU - Park, Se Won

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KW - Myrosinase

KW - Transgenic

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Engineering glucosinolates in plants: Current knowledge and potential uses

Abstract

Keywords

ASJC Scopus subject areas

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