Abstract
Estrone has been converted to an aminopyrimidino [17,16-e]-annelated estrane derivative. A number of amino acids dipeptides and tripeptides have been linked to the aminopyrimidino unit of the annelated steroid. The tripeptide motifs may be used for the complexation of metals, such as of technetium as a radio label for the potential detection of estrogen positive breast cancer cells.
Original language | English |
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Pages (from-to) | 391-396 |
Number of pages | 6 |
Journal | Journal of Chemical Research |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2009 |
Keywords
- Breast cancer
- Diagnostic agents
- Estranes
- Steroids
ASJC Scopus subject areas
- General Chemistry