Evaluation of 13 rapidly mutating Y-STRs on a Dravidian pedigree

S. Iyavoo, R. Alghafri, R. Almheiri, T. Haizel

Research output: Contribution to journalArticlepeer-review


The effectiveness of a rapidly mutating Y-STRs multiplex assay (RM Y-STRs) containing 13 RM Y-STR markers was compared with the AmpFℓSTR™ Yfiler™ PCR Amplification Kit (Yfiler) with conventional Y-STR markers for their efficiency in differentiating males within the same paternal lineage. Samples from 4 generations comprising 16 Dravidian males (15 father-son pairs) were analysed with both assays. Mutations were observed in 3 father-son pairs in the RM Y-STRs profiles while only 2 mutations were observed in the Y-filer profiles. Even though not many mutations were observed as anticipated, this study still emphasised the importance of RM Y-STRs when differentiation between males within the same paternal lineage is required and also indicated the need for mutation rates for different populations.

Original languageEnglish
Pages (from-to)216-217
Number of pages2
JournalForensic Science International: Genetics Supplement Series
Issue number1
Publication statusPublished - Dec 2019


  • Dravidian pedigree
  • Multiplex assay
  • Mutation
  • Rapidly mutating Y-STRs

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Genetics


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