Evolution of the insulin molecule: Insights into structure-activity and phylogenetic relationships

Keyphrases

• Insulin 100%
• Phylogenetic Relationship 100%
• Structure-activity Relationship 100%
• Receptor Binding Domain 33%
• Vertebrate Evolution 22%
• Structural Features 22%
• Receptor Binding 22%
• Amino Acids 11%
• Cysteine 11%
• Amino Acid Residues 11%
• Amino Acid Sequence 11%
• Evolutionary 11%
• Cladistic Analysis 11%
• Biologically Active 11%
• Hagfish 11%
• Binding Conformation 11%
• Mutagenesis Studies 11%
• Petromyzontiformes 11%
• Active Conformation 11%
• Alanine Scanning mutagenesis 11%
• Conserved Residues 11%
• Dipnoi 11%
• Vertebrate Species 11%
• Elasmobranchii 11%
• Invariant Residues 11%
• Crystalline State 11%
• Holocephali 11%
• Phylogenetic Inference 11%
• GluA4 11%
• Hystricomorph 11%
• CRISTAL 11%

Biochemistry, Genetics and Molecular Biology

• Cladistics 100%
• Insulin 100%
• Receptor Binding 71%
• Conformation 42%
• Amino Acids 28%
• Peptide Sequence 28%
• Binding Domain 28%
• Insulin Analog 28%
• Holocephali 28%
• Binding Site 14%
• Hagfish 14%
• Crystal Structure 14%
• Elasmobranch 14%
• Lungfish 14%
• Mutagenesis 14%
• Taxon 14%
• Cysteine 14%
• Alanine 14%