Exosome-coated metal-organic framework nanoparticles: An efficient drug delivery platform

Bernhard Illes, Patrick Hirschle, Sabine Barnert, Valentina Cauda, Stefan Wuttke, Hanna Engelke

Research output: Contribution to journalArticlepeer-review

194 Citations (Scopus)

Abstract

Exosomes might provide additional important advantages as compared to artificial lipid layers as a capping system. They are endogenous liposomes present in many body liquids. They supposedly are nonimmunogenic and are used by cells for communication purposes. They combine the advantages of a lipid bilayer with a potential shielding from the immune system and, unlike artificial lipid bilayers, they have a not yet understood endogenous mechanism that supports release from the endosomal entrapment.

Original languageEnglish
Pages (from-to)8042-8046
Number of pages5
JournalChemistry of Materials
Volume29
Issue number19
DOIs
Publication statusPublished - Oct 10 2017
Externally publishedYes

ASJC Scopus subject areas

  • General Chemistry
  • General Chemical Engineering
  • Materials Chemistry

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